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Methylation and PTEN activation in dental pulp mesenchymal stem cells promotes osteogenesis and reduces oncogenesis
Wen Ching Shen
, Yung Chih Lai
, Ling Hui Li
, Kolin Liao
, Hung Chang Lai
,
Shou Yen Kao
, John Wang
, Cheng Ming Chuong
, Shih Chieh Hung
*
*
此作品的通信作者
牙醫學院
研究成果
:
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同行評審
125
引文 斯高帕斯(Scopus)
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Keyphrases
Human Mesenchymal Stem Cells (hMSCs)
100%
Osteogenesis
100%
Oncogenesis
100%
Methylation
100%
Dental Mesenchymal Stem Cells
100%
Tumorigenesis
75%
Lineage Commitment
75%
Stem Cells
50%
Mesenchymal Stem Cells
25%
Adipocyte Differentiation
25%
Stem Cell-derived
25%
Bone Marrow
25%
Osteogenic Potential
25%
PI3K-Akt Pathway
25%
Therapeutic Use
25%
DNA Methyltransferase 3B (DNMT3B)
25%
DNA Methylation (DNAm)
25%
H3K9me3
25%
Methylation Status
25%
Differentiation Pathway
25%
Human Dental Pulp
25%
RNA-seq Expression
25%
Differential Expression Analysis
25%
Osteoblast Differentiation
25%
PTEN Expression
25%
Oncogenic Transformation
25%
Adipogenic Potential
25%
Epigenetic Factors
25%
Bone Marrow Neoplasms
25%
Dentin-pulp
25%
Biochemistry, Genetics and Molecular Biology
Bone Development
100%
Stem Cell
100%
Carcinogenesis
100%
Methylation
100%
Adipocyte
25%
Promoter Region
25%
DNA Methylation
25%
Osteoblast
25%
RNA Sequencing
25%
Epigenetics
25%
Expression Analysis
25%
DNMT3B
25%