Metasurface-Based Abrupt Autofocusing Beam for Biomedical Applications

Yuan Luo; Ming Lun Tseng; Sunil Vyas; Hsin Yu Kuo; Cheng Hung Chu; Mu Ku Chen; Hsiang Chieh Lee; Wen Pin Chen; Vin Cent Su; Xu Shi; Hiroaki Misawa; Din Ping Tsai; Pan Chyr Yang

doi:10.1002/smtd.202101228

Metasurface-Based Abrupt Autofocusing Beam for Biomedical Applications

Yuan Luo^*, Ming Lun Tseng, Sunil Vyas, Hsin Yu Kuo, Cheng Hung Chu, Mu Ku Chen, Hsiang Chieh Lee, Wen Pin Chen, Vin Cent Su, Xu Shi, Hiroaki Misawa, Din Ping Tsai, Pan Chyr Yang

^*此作品的通信作者

電子研究所

研究成果: Article › 同行評審

5 引文斯高帕斯（Scopus）

摘要

Manipulation and precise delivery of optical energies in the regions of interest within specimens require different strategies. Hence, proper control of input beam parameters is a prerequisite. One of the prominent methods is metasurface optics, capable of crafting properties of light at nanoscales. Here, the generation of an abrupt autofocusing (AAF) beam by a nanophotonic metasurface for biomedical applications is demonstrated. Fluorescence guided laser microprofiling of mouse cardiac samples is experimentally investigated, using the AAF beam to deliver optical energy selectively to specific locations. In addition, photocoagulation of ex vivo swine skin tissue is performed and observed through optical coherence tomography. The results show great potentials for integrating metasurface optics to realize miniature laser surgery instruments for wide applications in biomedicine.

原文	English
期刊	Small Methods
DOIs	https://doi.org/10.1002/smtd.202101228
出版狀態	Accepted/In press - 2022

存取文件

10.1002/smtd.202101228

其它文件與鏈接

Link to publication in Scopus

引用此

@article{0f495f9fb72a46a080f87452dcb4ba4c,

title = "Metasurface-Based Abrupt Autofocusing Beam for Biomedical Applications",

abstract = "Manipulation and precise delivery of optical energies in the regions of interest within specimens require different strategies. Hence, proper control of input beam parameters is a prerequisite. One of the prominent methods is metasurface optics, capable of crafting properties of light at nanoscales. Here, the generation of an abrupt autofocusing (AAF) beam by a nanophotonic metasurface for biomedical applications is demonstrated. Fluorescence guided laser microprofiling of mouse cardiac samples is experimentally investigated, using the AAF beam to deliver optical energy selectively to specific locations. In addition, photocoagulation of ex vivo swine skin tissue is performed and observed through optical coherence tomography. The results show great potentials for integrating metasurface optics to realize miniature laser surgery instruments for wide applications in biomedicine.",

keywords = "abrupt autofocusing beam, laser surgery, metasurfaces",

author = "Yuan Luo and Tseng, {Ming Lun} and Sunil Vyas and Kuo, {Hsin Yu} and Chu, {Cheng Hung} and Chen, {Mu Ku} and Lee, {Hsiang Chieh} and Chen, {Wen Pin} and Su, {Vin Cent} and Xu Shi and Hiroaki Misawa and Tsai, {Din Ping} and Yang, {Pan Chyr}",

note = "Publisher Copyright: {\textcopyright} 2022 The Authors. Small Methods published by Wiley-VCH GmbH",

year = "2022",

doi = "10.1002/smtd.202101228",

language = "English",

journal = "Small Methods",

issn = "2366-9608",

publisher = "John Wiley and Sons Ltd",

}

TY - JOUR

T1 - Metasurface-Based Abrupt Autofocusing Beam for Biomedical Applications

AU - Luo, Yuan

AU - Tseng, Ming Lun

AU - Vyas, Sunil

AU - Kuo, Hsin Yu

AU - Chu, Cheng Hung

AU - Chen, Mu Ku

AU - Lee, Hsiang Chieh

AU - Chen, Wen Pin

AU - Su, Vin Cent

AU - Shi, Xu

AU - Misawa, Hiroaki

AU - Tsai, Din Ping

AU - Yang, Pan Chyr

PY - 2022

Y1 - 2022

N2 - Manipulation and precise delivery of optical energies in the regions of interest within specimens require different strategies. Hence, proper control of input beam parameters is a prerequisite. One of the prominent methods is metasurface optics, capable of crafting properties of light at nanoscales. Here, the generation of an abrupt autofocusing (AAF) beam by a nanophotonic metasurface for biomedical applications is demonstrated. Fluorescence guided laser microprofiling of mouse cardiac samples is experimentally investigated, using the AAF beam to deliver optical energy selectively to specific locations. In addition, photocoagulation of ex vivo swine skin tissue is performed and observed through optical coherence tomography. The results show great potentials for integrating metasurface optics to realize miniature laser surgery instruments for wide applications in biomedicine.

AB - Manipulation and precise delivery of optical energies in the regions of interest within specimens require different strategies. Hence, proper control of input beam parameters is a prerequisite. One of the prominent methods is metasurface optics, capable of crafting properties of light at nanoscales. Here, the generation of an abrupt autofocusing (AAF) beam by a nanophotonic metasurface for biomedical applications is demonstrated. Fluorescence guided laser microprofiling of mouse cardiac samples is experimentally investigated, using the AAF beam to deliver optical energy selectively to specific locations. In addition, photocoagulation of ex vivo swine skin tissue is performed and observed through optical coherence tomography. The results show great potentials for integrating metasurface optics to realize miniature laser surgery instruments for wide applications in biomedicine.

KW - abrupt autofocusing beam

KW - laser surgery

KW - metasurfaces

UR - http://www.scopus.com/inward/record.url?scp=85125187854&partnerID=8YFLogxK

U2 - 10.1002/smtd.202101228

DO - 10.1002/smtd.202101228

M3 - Article

C2 - 35212186

AN - SCOPUS:85125187854

SN - 2366-9608

JO - Small Methods

JF - Small Methods

ER -

Metasurface-Based Abrupt Autofocusing Beam for Biomedical Applications

摘要

存取文件

其它文件與鏈接

指紋

引用此