@inbook{e6a0849c01d349cdbd274d4a8729e09d,
title = "Metabolic Engineering Design Strategies for Increasing Carbon Fluxes Relevant for Biosynthesis in Cyanobacteria",
abstract = "Cyanobacteria are promising microbial cell factories for the direct production of biochemicals and biofuels from CO2. Through genetic and metabolic engineering, they can be modified to produce a variety of both natural and non-natural compounds. To enhance the yield of these products, various design strategies have been developed. In this chapter, strategies used to enhance metabolic fluxes towards common precursors used in biosynthesis, including pyruvate, acetyl-CoA, malonyl-CoA, TCA cycle intermediates, and aromatics, are discussed. Additionally, strategies related to cofactor availability and mixotrophic conditions for bioproduction are also summarize.",
keywords = "Carbon flux, Central metabolites, Cyanobacteria, Design strategies, Metabolic engineering",
author = "Chen, {Arvin Y.} and Ku, {Jason T.} and Tsai, {Teresa P.} and Hung, {Jenny J.} and Hung, {Billy C.} and Lan, {Ethan I.}",
note = "Publisher Copyright: {\textcopyright} 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.",
year = "2023",
doi = "10.1007/10_2023_218",
language = "English",
series = "Advances in Biochemical Engineering/Biotechnology",
publisher = "Springer Science and Business Media Deutschland GmbH",
pages = "105--144",
booktitle = "Advances in Biochemical Engineering/Biotechnology",
address = "德國",
}