Matrix-assisted laser desorption ionization-time of flight mass spectrometry accelerates pathogen identification and may confer benefit in the outcome of peritoneal dialysis-related peritonitis

Wei Hung Lin; Jyh Chang Hwang; Chin Chung Tseng; Yu Tzu Chang; An Bang Wu; Jing Jou Yan; Jiunn Jong Wu; Ming Cheng Wang

doi:10.1128/JCM.03378-15

Matrix-assisted laser desorption ionization-time of flight mass spectrometry accelerates pathogen identification and may confer benefit in the outcome of peritoneal dialysis-related peritonitis

Wei Hung Lin
, Jyh Chang Hwang
, Chin Chung Tseng
, Yu Tzu Chang
, An Bang Wu
, Jing Jou Yan
, Jiunn Jong Wu
, Ming Cheng Wang^*

^*此作品的通信作者

醫學生物技術暨檢驗學系

研究成果: Article › 同行評審

11 引文斯高帕斯（Scopus）

摘要

Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) and conventional standard methods were compared for time to pathogen identification and impact on clinical outcomes in peritoneal dialysis-related peritonitis patients. The MALDI-TOF MS method identified the causative microorganisms earlier (average time saved, 64 h for all pathogens), and patients had a shorter hospital stay (mean±standard deviation, 5.2±4.8 days versus 8.2±4.5 days, P=0.001).

原文	English
頁（從 - 到）	1381-1383
頁數	3
期刊	Journal of Clinical Microbiology
卷	54
發行號	5
DOIs	https://doi.org/10.1128/JCM.03378-15
出版狀態	Published - 5月 2016

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10.1128/JCM.03378-15

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Lin, W. H., Hwang, J. C., Tseng, C. C., Chang, Y. T., Wu, A. B., Yan, J. J., Wu, J. J., & Wang, M. C. (2016). Matrix-assisted laser desorption ionization-time of flight mass spectrometry accelerates pathogen identification and may confer benefit in the outcome of peritoneal dialysis-related peritonitis. Journal of Clinical Microbiology, 54(5), 1381-1383. https://doi.org/10.1128/JCM.03378-15

@article{5cb3a15f056b477b880f8623b417fc7e,

title = "Matrix-assisted laser desorption ionization-time of flight mass spectrometry accelerates pathogen identification and may confer benefit in the outcome of peritoneal dialysis-related peritonitis",

abstract = "Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) and conventional standard methods were compared for time to pathogen identification and impact on clinical outcomes in peritoneal dialysis-related peritonitis patients. The MALDI-TOF MS method identified the causative microorganisms earlier (average time saved, 64 h for all pathogens), and patients had a shorter hospital stay (mean±standard deviation, 5.2±4.8 days versus 8.2±4.5 days, P=0.001).",

author = "Lin, \{Wei Hung\} and Hwang, \{Jyh Chang\} and Tseng, \{Chin Chung\} and Chang, \{Yu Tzu\} and Wu, \{An Bang\} and Yan, \{Jing Jou\} and Wu, \{Jiunn Jong\} and Wang, \{Ming Cheng\}",

year = "2016",

month = may,

doi = "10.1128/JCM.03378-15",

language = "English",

volume = "54",

pages = "1381--1383",

journal = "Journal of Clinical Microbiology",

issn = "0095-1137",

publisher = "American Society for Microbiology",

number = "5",

}

Lin, WH, Hwang, JC, Tseng, CC, Chang, YT, Wu, AB, Yan, JJ, Wu, JJ & Wang, MC 2016, 'Matrix-assisted laser desorption ionization-time of flight mass spectrometry accelerates pathogen identification and may confer benefit in the outcome of peritoneal dialysis-related peritonitis', Journal of Clinical Microbiology, 卷 54, 編號 5, 頁 1381-1383. https://doi.org/10.1128/JCM.03378-15

Matrix-assisted laser desorption ionization-time of flight mass spectrometry accelerates pathogen identification and may confer benefit in the outcome of peritoneal dialysis-related peritonitis. / Lin, Wei Hung; Hwang, Jyh Chang; Tseng, Chin Chung 等.
於: Journal of Clinical Microbiology, 卷 54, 編號 5, 05.2016, p. 1381-1383.

研究成果: Article › 同行評審

TY - JOUR

T1 - Matrix-assisted laser desorption ionization-time of flight mass spectrometry accelerates pathogen identification and may confer benefit in the outcome of peritoneal dialysis-related peritonitis

AU - Lin, Wei Hung

AU - Hwang, Jyh Chang

AU - Tseng, Chin Chung

AU - Chang, Yu Tzu

AU - Wu, An Bang

AU - Yan, Jing Jou

AU - Wu, Jiunn Jong

AU - Wang, Ming Cheng

PY - 2016/5

Y1 - 2016/5

N2 - Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) and conventional standard methods were compared for time to pathogen identification and impact on clinical outcomes in peritoneal dialysis-related peritonitis patients. The MALDI-TOF MS method identified the causative microorganisms earlier (average time saved, 64 h for all pathogens), and patients had a shorter hospital stay (mean±standard deviation, 5.2±4.8 days versus 8.2±4.5 days, P=0.001).

AB - Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) and conventional standard methods were compared for time to pathogen identification and impact on clinical outcomes in peritoneal dialysis-related peritonitis patients. The MALDI-TOF MS method identified the causative microorganisms earlier (average time saved, 64 h for all pathogens), and patients had a shorter hospital stay (mean±standard deviation, 5.2±4.8 days versus 8.2±4.5 days, P=0.001).

UR - https://www.scopus.com/pages/publications/84964937836

U2 - 10.1128/JCM.03378-15

DO - 10.1128/JCM.03378-15

M3 - Article

C2 - 26912750

AN - SCOPUS:84964937836

SN - 0095-1137

VL - 54

SP - 1381

EP - 1383

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

IS - 5

ER -

Matrix-assisted laser desorption ionization-time of flight mass spectrometry accelerates pathogen identification and may confer benefit in the outcome of peritoneal dialysis-related peritonitis

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