Mapping billions of short reads to a reference genome

Jui-Hung Hung, Zhiping Weng

研究成果: Article同行評審

2 引文 斯高帕斯(Scopus)

摘要

Rapid development and commercialization of instruments that can accurately, rapidly, and cheaply sequence billions of DNA bases is revolutionizing molecular biology and medicine. Because a reference genome is usually available, the first bioinformatics challenge presented by the new generation of highthroughput sequencers is the genome mapping problem, where each read is mapped to a reference genome to reveal its location(s). An introduction to mapping algorithms, as well as factors that influence their results, is provided here.

原文English
頁(從 - 到)14-17
頁數4
期刊Cold Spring Harbor Protocols
2017
發行號1
DOIs
出版狀態Published - 1 一月 2017

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