Loss of RUNX3 increases osteopontin expression and promotes cell migration in gastric cancer

Keyphrases

• Binding Site 5%
• Cell Migration 100%
• Chromatin Immunoprecipitation (ChIP) 5%
• Clinical Specimens 11%
• Co-expression 5%
• Direct Binding 5%
• Ectopic Expression 5%
• Epithelial Cell Line 5%
• Gastric Cancer 100%
• Gastric Cancer Cell Lines 5%
• Gastric Cancer Cells 5%
• Gastric Cancer Patients 5%
• Gastric Epithelial Cells 5%
• GES-1 5%
• GES-1 Cells 5%
• Green Fluorescent Protein 5%
• Knockdown 23%
• Lymph Node Metastasis 5%
• Messenger RNA Expression 11%
• Metastasis Prognosis 5%
• Migration Ability 5%
• Molecular Mechanism 5%
• Osteopontin 64%
• Osteopontin Expression 100%
• Overexpression 5%
• Poor Prognosis 11%
• Promoter Activity 5%
• Promoter Region 5%
• Protein Level 5%
• RNA-protein Complex 5%
• Runt-related Transcription Factor 3 (RUNX3) 100%
• Specific Binding 5%
• Transcriptional Repressor 5%
• Tumor 5%

Biochemistry, Genetics and Molecular Biology

• Binding Site 6%
• Cancer Cell 12%
• Cell Migration 100%
• Chromatin Immunoprecipitation 6%
• Ectopic Expression 6%
• Green Fluorescent Protein 6%
• Messenger RNA 12%
• Osteopontin 100%
• Promoter Region 18%
• RUNX3 100%
• Transcription Factor RUNX3 6%
• Transcriptional Repressor 6%