TY - GEN
T1 - Locating optimal electrodes placement via microelectrode recording in general anesthetic patients during deep brain stimulation
AU - Chuang, Wei Yi
AU - Young, Kuu-Young
AU - Chao, Paul C.-P.
AU - Tsai, Sheng Tzung
AU - Chen, Shin Yuan
PY - 2012
Y1 - 2012
N2 - Deep brain stimulation (DBS) is one of promising therapy to treat advanced Parkinson's disease. During DBS operation, general anesthetic induction has been shown an alternative procedure to avoid patient's discomfort under local anesthesia. Meanwhile, microelectrode recording (MER) is a guide of optimal placement in the brain. However, the inhibition of power of neural spiking is assumed by the general anesthesia during the process. Therefore, we use median nerve stimulation (MNS) to enhance them. At the same time, the power of background noise is also enhanced. Then, it makes MER be poor to determine the optimal electrode placement. In this study, we present a methodology including spike detection, fast Fourier transformation and power spectrum analysis for analyzing MER. Through these results, MER data can be successfully utilized for tracking dorsolateral sub thalamic nucleus (STN) to ensure optimal electrode location.
AB - Deep brain stimulation (DBS) is one of promising therapy to treat advanced Parkinson's disease. During DBS operation, general anesthetic induction has been shown an alternative procedure to avoid patient's discomfort under local anesthesia. Meanwhile, microelectrode recording (MER) is a guide of optimal placement in the brain. However, the inhibition of power of neural spiking is assumed by the general anesthesia during the process. Therefore, we use median nerve stimulation (MNS) to enhance them. At the same time, the power of background noise is also enhanced. Then, it makes MER be poor to determine the optimal electrode placement. In this study, we present a methodology including spike detection, fast Fourier transformation and power spectrum analysis for analyzing MER. Through these results, MER data can be successfully utilized for tracking dorsolateral sub thalamic nucleus (STN) to ensure optimal electrode location.
KW - Deep brain stimulation (DBS)
KW - dorsolateral subthalamic nucleus (STN)
KW - general anesthetic
KW - median nerve stimulation (MNS)
KW - microelectrode recording (MER)
UR - http://www.scopus.com/inward/record.url?scp=84866652809&partnerID=8YFLogxK
U2 - 10.1109/iCBEB.2012.266
DO - 10.1109/iCBEB.2012.266
M3 - Conference contribution
AN - SCOPUS:84866652809
SN - 9780769547060
T3 - Proceedings - 2012 International Conference on Biomedical Engineering and Biotechnology, iCBEB 2012
SP - 1048
EP - 1051
BT - Proceedings - 2012 International Conference on Biomedical Engineering and Biotechnology, iCBEB 2012
T2 - 2012 International Conference on Biomedical Engineering and Biotechnology, iCBEB 2012
Y2 - 28 May 2012 through 30 May 2012
ER -