Label-free optofluidic biomolecular sensing using a photonic crystal nanotweezer: The wiggle assay

Pilgyu Kang*, Yih Fan Chen, David Erickson

*此作品的通信作者

研究成果: Conference contribution同行評審

摘要

Here we introduce a novel optofluidic biosensing method using a nanotweezer which allows a simple and rapid biological assay. Optical biosensing methods have provided necessities that biosensors needed such as high sensitivity and specificity with a price. The methodology we present rely on an optical trapping and an observation with epifluorescent microscopy. We utilize an optical trap and observe a change of the trap stiffness, which is sensitive to the change of the size of an optically trapped particle caused by the binding of label-free target biomolecules. We have demonstrated reliability and consistency of our sensing method with experimental results.

原文English
主出版物標題17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
發行者Chemical and Biological Microsystems Society
頁面1388-1390
頁數3
ISBN(列印)9781632666246
出版狀態Published - 2013
事件17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
持續時間: 27 10月 201331 10月 2013

出版系列

名字17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
3

Conference

Conference17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
國家/地區Germany
城市Freiburg
期間27/10/1331/10/13

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