Johnson-Kendall-Roberts theory applied to living cells

Y. S. Chu*, S. Dufour, J. P. Thiery, E. Ferez, F. Pincet

*此作品的通信作者

研究成果: Conference contribution同行評審

摘要

The Johnson-Kendall-Roberts (JKR) theory is an accurate model for of soft deformable materials with strong adhesion energies. Little is known about the validity of this theory on complex systems such as living cells. We have addressed this question using a depletion controlled cell adhesion and measured the force necessary to separate the cells with a micropipette technique. We show that the cytoskeleton can provide the cells with a 3D structure that is sufficiently elastic and has a sufficiently low deformability for JICR theory to be valid. When the cytoskeleton is disrupted, JKR theory is no longer applicable.

原文English
主出版物標題2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005 Technical Proceedings
編輯M. Laudon, B. Romanowicz
頁面560-562
頁數3
出版狀態Published - 5月 2005
事件2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005 - Anaheim, CA, United States
持續時間: 8 5月 200512 5月 2005

出版系列

名字2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005 Technical Proceedings

Conference

Conference2005 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2005
國家/地區United States
城市Anaheim, CA
期間8/05/0512/05/05

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