Is vasospasm requisite for posterior leukoencephalopathy in patients with primary thunderclap headaches?

S. P. Chen, J. L. Fuh, J. F. Lirng, S. J. Wang*

*此作品的通信作者

研究成果: Review article同行評審

33 引文 斯高帕斯(Scopus)

摘要

Primary thunderclap headache (TCH) is sometimes associated with cerebral vasospasm. However, the role of vasospasm in relation to the development of reversible or irreversible posterior leukoencephalopathy among patients with primary TCH has never been fully addressed. This paper includes a report on a 51-year-old woman with primary TCH complicated with posterior leukoencephalopathy and a literature review of 16 further patients with the same illness. Their magnetic resonance or conventional angiographic findings were clearly described. Our review found that all these 17 patients showed evidence of cerebral vasospasm. Eleven (65%) of them developed permanent ischaemic infarctions, almost exclusively located at the watershed zones. We suggest that the presence of vasospasm might be requisite for posterior leukoencephalopathy as well as for permanent infarctions in these patients. Therefore, searching for any clue of vasospasm is mandatory in treatment of patients with primary TCH. Absence of an accompanying vasospasm might predict a good outcome.

原文English
頁(從 - 到)530-536
頁數7
期刊Cephalalgia
26
發行號5
DOIs
出版狀態Published - 5月 2006

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