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Interfering B cell receptor signaling via SHP-1/p-Lyn axis shows therapeutic potential in diffuse large B-cell lymphoma
Ji Lin Chen
, Pei Yi Chu
, Chun Teng Huang
, Tzu Ting Huang
, Wan Lun Wang
, Yu Hsuan Lee
, Yuan Ya Chang
, Ming Shen Dai
, Chung Wai Shiau
,
Chun Yu Liu
*
*
此作品的通信作者
生物藥學研究所
醫學系內科學科
研究成果
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同行評審
6
引文 斯高帕斯(Scopus)
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Keyphrases
Therapeutic Potential
100%
Diffuse Large B-cell Lymphoma (DLBCL)
100%
B-cell Receptor Signaling
100%
SHP-1
100%
Immunohistochemical Staining
12%
Negatively Regulate
12%
Ibrutinib
12%
Therapeutic Implications
6%
Potential Therapeutics
6%
Apoptosis
6%
Biological Function
6%
Phosphorylation
6%
Xenograft
6%
Antitumor Effect
6%
Cell Apoptosis
6%
Antiproliferative Activity
6%
Western Blot Analysis
6%
Oral Administration
6%
In Vitro Study
6%
Anti-apoptosis
6%
Tumor Suppressive Role
6%
New Drug Targets
6%
Protein Tyrosine Phosphatase 1B (PTP1B)
6%
Phosphatase Activity
6%
Diffuse Large B-cell Lymphoma Cells
6%
Protein Phosphatase
6%
Non-Hodgkin Lymphoma
6%
Phosphatase Assay
6%
H-score
6%
Tyrosine Kinase Oncogene
6%
Bruton Tyrosine Kinase Inhibitor
6%
Pharmacology, Toxicology and Pharmaceutical Science
Diffuse Large B Cell Lymphoma
100%
B Lymphocyte Receptor
100%
Neoplasm
28%
Protein Tyrosine Phosphatase SHP 1
28%
Ibrutinib
28%
Western Blot
14%
Protein Tyrosine Kinase
14%
Protein Tyrosine Phosphatase
14%
Phosphoprotein Phosphatase
14%
Nonhodgkin Lymphoma
14%
Bruton Tyrosine Kinase Inhibitor
14%