Immunomodulatory effects of far-infrared ray irradiation via increasing calmodulin and nitric oxide production in raw 264.7 macrophages

Ting Kai Leung, Yung Sheng Lin*, Yen Chou Chen, Huey Fang Shang, Yi Hsuan Lee, Ching Hua Su, Huang Chu Liao, Tsong Min Chang

*此作品的通信作者

研究成果: Article同行評審

29 引文 斯高帕斯(Scopus)

摘要

Far-infrared ray (FIR) radiation has been shown to be beneficial to human health; however, little scientific evidence of its mechanisms has been provided. In the present study, we investigated the effect of nonthermal-enhanced FIR on the expression of calmodulin (Cam) protein and nitric oxide (NO) production by RAW 264.7 macrophages. Results indicated a significant increase in Cam protein in FIR-treated RAW 264.7 macrophages with or without the addition of lipopolysaccharide (LPS). In addition, the amount of NO was slightly higher but increased significantly in FIR plus LPS-treated RAW 264.7 macrophages. Data of the present study provide the first evidence to indicate the immunomodulatory properties of FIR through increasing Cam protein and NO production in RAW 264.7 macrophages.

原文English
頁(從 - 到)317-323
頁數7
期刊Biomedical Engineering - Applications, Basis and Communications
21
發行號5
DOIs
出版狀態Published - 10月 2009

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