Immunoglobulin M antibodies against hepatitis C virus antigens: significance and applications

Pei Jer Chen*, Lih Hwa Hwang, Li Yen Chang, Jia Horng Kao, Ding Shinn Chen

*此作品的通信作者

研究成果: Article同行評審

摘要

The immunoglobulin M antibody against hepatitis C viral capsid (core) antigen has been found to be a possible marker for acute infection in posttransfusion hepatitis C. We extended this observation to a spoadic hepatitis C. In addition, a modified recombinant immunoblot assay (RIBA) that contained three HCV antigens (capsid, NS3 and NS5) in one strip was developed and used to study the antibody response among patients. This allowed a simultaneous comparison of either immunoglobulin M or G specific to individual HCV antigen and yielded more information. The assay was found useful in the diagnosis of acute hepatitis C in clinically uncertain cases.

原文English
頁(從 - 到)67-70
頁數4
期刊Gastroenterologia Japonica
28
發行號5 Supplement
DOIs
出版狀態Published - 5月 1993

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