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Hepatoprotective effects of naturally fermented noni juice against thioacetamide-induced liver fibrosis in rats
Yi Ling Lin
, Hui Wen Lin
, Yi Chen Chen
,
Deng Jye Yang
, Chien Chun Li
, Yuan Yen Chang
*
*
此作品的通信作者
食品安全及健康風險評估研究所
研究成果
:
Article
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同行評審
33
引文 斯高帕斯(Scopus)
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Keyphrases
Thioacetamide
100%
Hepatoprotective
100%
Liver Fibrosis
100%
Noni Fruit
100%
Reactive Oxygen Species
22%
Liver
22%
Matrix metalloproteinase-2 (MMP-2)
22%
Matrix metalloproteinase-9 (MMP-9)
22%
Tissue Inhibitor of metalloproteinase-1 (TIMP-1)
22%
Endoplasmic Reticulum Stress (ER stress)
22%
Inflammation
11%
Inflammatory Cytokines
11%
High Dose
11%
Aspartate Aminotransferase
11%
Rat Model
11%
Collagen
11%
Collagen Content
11%
Protective Effect
11%
Extracellular Matrix Protein 1 (ECM1)
11%
Liver Tissue
11%
Hepatic Antioxidants
11%
Collagen Matrix
11%
Serum Alanine Aminotransferase
11%
Antioxidant Capacity
11%
Low Body Weight
11%
TIMP3
11%
Stress-related Gene Expression
11%
Cytokine Secretion
11%
Hepatic Stellate Cells
11%
Nutraceuticals
11%
Liver Weight
11%
Morinda Citrifolia
11%
Serum Lipids
11%
Collagen Accumulation
11%
Protection Potential
11%
Pharmacology, Toxicology and Pharmaceutical Science
Thioacetamide-Induced Liver Fibrosis
100%
Morinda citrifolia
100%
Thioacetamide
70%
Tissue Inhibitor of Metalloproteinase
30%
Cytokine
20%
Reactive Oxygen Metabolite
20%
Gelatinase A
20%
Gelatinase B
20%
Antioxidant Capacity
20%
Liver Fibrosis
20%
Inflammation
10%
Matrix Metalloproteinase
10%
Aspartate Aminotransferase
10%
Alanine Aminotransferase
10%
Rat Model
10%
Scleroprotein
10%
Functional Food
10%
Biochemistry, Genetics and Molecular Biology
Thioacetamide
100%
Morinda citrifolia
100%
Metalloprotease Inhibitor
30%
Gelatinase A
20%
MMP2
20%
Gelatinase B
20%
MMP9
20%
Endoplasmic Reticulum Stress
20%
Gene Expression
10%
Low Drug Dose
10%
Aspartate Transaminase
10%
Cytokine Release
10%
Matrix Metalloproteinase
10%
Extracellular Matrix Proteins
10%
Scleroprotein
10%
Rat Model
10%
Drug Megadose
10%
Body Weight
10%
Alanine Aminotransferase Blood Level
10%
Inflammatory Cytokine
10%
Blood Lipids
10%
Hepatic Stellate Cell
10%
Food Science
Antioxidant Capacity
100%
Alanine
50%
Functional Food
50%
Protein Matrix
50%
Gene Expression
50%
Immunology and Microbiology
Morinda citrifolia
100%
Endoplasmic Reticulum Stress
20%
Inflammatory Cytokine
10%
Gene Expression
10%
Drug Megadose
10%
Cytokine Release
10%
Low Drug Dose
10%
Matrix Protein
10%
Extracellular Matrix
10%
Liver Tissue
10%
Alanine Aminotransferase Blood Level
10%
Body Weight
10%
Rat Model
10%
Lipid Level
10%
Lipid Blood Level
10%
Liver Weight
10%
Hepatic Stellate Cell
10%