Green synthesis of naphthyl derivative as an optical sensor for the detection of l-carnitine in food samples

Lavanya Raja, Srinivasadesikan Venkatesan, Ming Chang Lin, Padmini Vediappen*

*此作品的通信作者

研究成果: Review article同行評審

2 引文 斯高帕斯(Scopus)

摘要

An economical and green approach to the synthesis of naphthyl derivative for detection of l-carnitine (3-hydroxy-4-N-trimethyl-aminobutyrate) is practically important. We developed a naphthyl derivative as a probe showing ‘turn-on’ response towards l-carnitine selectively at pH 7.2 through ICT mechanism with a good limit of detection (LOD) of 0.126 μM. Using Job's plot for determining the binding stoichiometry, it was found that probe could form a more stable complex (1:1) with carnitine. The binding constant (K) between probe and carnitine was calculated as 8 × 107 M−1 using the Benesi–Hildebrand plot. The binding interaction of the probe with l-carnitine was confirmed by nuclear magnetic resonance titrations, Fourier-transform infrared spectroscopy, photo physical studies and density functional theory calculations. Meanwhile, the probe can be used to quantitatively detect carnitine in food samples.

原文English
頁(從 - 到)224-231
頁數8
期刊Luminescence
38
發行號3
DOIs
出版狀態Published - 3月 2023

指紋

深入研究「Green synthesis of naphthyl derivative as an optical sensor for the detection of l-carnitine in food samples」主題。共同形成了獨特的指紋。

引用此