Graphene oxide as broadband hyperthermic agent and chemo-photothermal dissolution of kidney-stone mimicking calcium oxalate crystals

Hung You Chen, Sandip Ghosh, Vinoth Kumar Ponnusamy, Surojit Chattopadhyay*

*此作品的通信作者

研究成果: Article同行評審

3 引文 斯高帕斯(Scopus)

摘要

Graphene oxide (GO) and gold nanorods (AuNRs) have been extensively evaluated for broadband (325-980 nm) photothermal (PT) heat generation and efficiency, on substrates having contrasting thermal conductivities. Infrared thermal imaging of the PT agents under broadband irradiation showed a maximum rise of local temperature of chicken kidney tissue by 16.4, and 5.7 °C for GO and AuNR, respectively, under similar irradiation conditions. The PT conversion efficiency, derived from the cooling curves of the dynamic PT response, was found to be exceeding 60 % for GO on chicken kidney tissue under 532, 785, and 980 nm laser irradiations. The PT effect was used to enhance the dissolution rate of the kidney stone mimicking calcium oxalate crystals in the presence of hydroxyanthraquinone (AQ) solution. Mass spectrometric experiments show that the combination of AQ and GO, when irradiated with 532 nm, could chemo-photothermally dissolve calcium oxalate by at least ∼20 % more than when using AQ alone, or using a resistive way of elevating the solution temperature.

原文English
文章編號112917
頁數9
期刊Journal of Photochemistry and Photobiology A: Chemistry
405
DOIs
出版狀態Published - 15 1月 2021

指紋

深入研究「Graphene oxide as broadband hyperthermic agent and chemo-photothermal dissolution of kidney-stone mimicking calcium oxalate crystals」主題。共同形成了獨特的指紋。

引用此