Gender-Related Differences in Patients Who Underwent Catheter Ablation of Atrial Fibrillation

Kazuyoshi Suenari, Yenn Jiang Lin, Shih Lin Chang, Li Wei Lo, Yu Feng Hu, Yukiko Nakano, Yasuki Kihara, Shih Ann Chen

研究成果: Article同行評審


Background: Gender differences in atrial fibrillation (AF) have not been fully elucidated. Methods: This study enrolled 297 consecutive patients (women/men 74/223) with symptomatic AF who underwent AF ablation using NavX system. The gender differences in the clinical parameters, atrial substrate properties, and clinical outcome in this population were studied. Results: Women were older, lower incidence of non-paroxysmal AF, and higher incidence of pure pulmonary vein (PV) triggers than men. Although there was no significant gender difference in the incidence of non-PV triggers, women had a higher incidence of pure superior vena cava triggers than men. Regarding the atrial substrate properties during sinus rhythm, women had lower peak-to-peak voltages in the right atrium and higher dominant frequencies (DFs) in both atria. In contrast, according to the high density mapping during AF, men had a shorter mean CFE and higher mean DF value in the left atrium. Kaplan-Meier analysis demonstrated that the sinus rhythm maintenance rate after AF ablation was similar between women and men at a mean follow-up of 18 ± 7 months. However, in the patient group with non-PV triggers (N=35), men had a significantly higher AF recurrence than women (P<0.05). Conclusion: This study demonstrated the gender-related differences in the clinical features and atrial substrate properties in AF patients.

頁(從 - 到)437
期刊journal of arrhythmia
出版狀態Published - 2011


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