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Fibronectin-LILRB4/gp49B interaction negatively regulates osteoclastogenesis through inhibition of RANKL-induced TRAF6/TAK1/NF-kB/MAPK signaling
Mei Tzu Su
*
, Karin Ono, Dai Kezuka, Shotaro Miyamoto, Yu Mori, Toshiyuki Takai
*
此作品的通信作者
醫學生物技術暨檢驗學系
研究成果
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同行評審
8
引文 斯高帕斯(Scopus)
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深入研究「Fibronectin-LILRB4/gp49B interaction negatively regulates osteoclastogenesis through inhibition of RANKL-induced TRAF6/TAK1/NF-kB/MAPK signaling」主題。共同形成了獨特的指紋。
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Keyphrases
Leukocytes
100%
Mitogen-activated Protein Kinase
100%
Nuclear factor-κB
100%
Negatively Regulate
100%
Immunoglobulin
100%
Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6)
100%
Fibronectin
100%
Osteoclastogenesis
100%
Like Receptors
100%
Phosphorylation
40%
Nuclear factor-B
40%
Osteoclast
40%
SHP-1
40%
Osteoclast Formation
40%
RAW264.7 Cells
20%
Transforming Growth Factor-β
20%
Wild Mice
20%
Bone Resorption
20%
Trabecular Bone
20%
Dysregulation
20%
Signal Transduction
20%
Protein Tyrosine Phosphatase 1B (PTP1B)
20%
Orthologs
20%
Immune Regulation
20%
Inhibitory Receptors
20%
Differentiation in Vitro
20%
SH3 Domain
20%
Osteoclast Differentiation
20%
Receptor Activator of nuclear factor-B Ligand
20%
Bone Disorders
20%
Multinucleated Cells
20%
Leukocyte Immune-type Receptors
20%
Medicine and Dentistry
Leukocyte
100%
Receptor
100%
Mitogen-Activated Protein Kinase
100%
Phosphotransferase
100%
Kinase Signaling
100%
Immunoglobulin
100%
Fibronectin
100%
Osteoclastogenesis
100%
Osteoclast Differentiation Factor
100%
Tumor Necrosis Factor Receptor Associated Factor 6
100%
Nuclear Factor I
100%
Alternative Complement Pathway C3 C5 Convertase
27%
Osteoclast
18%
In Vitro
9%
Amino Terminal Sequence
9%
Osteolysis
9%
Nuclear Factor
9%
Cancellous Bone
9%
Orthology
9%
Protein Tyrosine Phosphatase
9%
Immunoregulation
9%
Cancer Growth Factor
9%
Bone Disease
9%
Biochemistry, Genetics and Molecular Biology
Phosphotransferase
100%
Kinase
100%
Leukocyte
100%
Intravenous Immunoglobulin
100%
Mitogen-Activated Protein Kinase
100%
Tumor Necrosis Factor Receptor
100%
Osteoclastogenesis
100%
RANKL
100%
Nuclear Factor I
100%
Fibronectin
100%
Complement Factor B
30%
Osteoclast
20%
N-Terminus
10%
Osteolysis
10%
Protein Tyrosine Phosphatase
10%
Orthology
10%
Wild Type Mouse
10%
Immunoregulation
10%
Leukocyte Immunoglobulin-Like Receptors
10%
Cancer Growth Factor
10%
Immunology and Microbiology
Leukocyte
100%
Tumor Necrosis Factor Receptor
100%
Intravenous Immunoglobulin
100%
Mitogen
100%
Osteoclastogenesis
100%
RANKL
100%
Nuclear Factor I
100%
Fibronectin
100%
Complement Factor B
30%
Osteoclast
20%
Amino Terminal Sequence
10%
Wild Type Mouse
10%
Osteolysis
10%
Immunoregulation
10%
Orthology
10%
Trabecular Bone
10%
Leukocyte Immunoglobulin-Like Receptors
10%
Cancer Growth Factor
10%
Tyrosine
10%
Pharmacology, Toxicology and Pharmaceutical Science
Receptor
100%
Phosphotransferase
100%
Mitogen Activated Protein Kinase
100%
Immunoglobulin
100%
Tumor Necrosis Factor Receptor Associated Factor 6
100%
Fibronectin
100%
Osteoclast Differentiation Factor
100%
Nuclear Factor I
100%
Alternative Complement Pathway C3 C5 Convertase
27%
Wild Type Mouse
9%
Protein Tyrosine Phosphatase
9%
Nuclear Factor
9%
Cancer Growth Factor
9%
Bone Disease
9%