Fatal Fulminant Cerebral Edema in Six Children With SARS-CoV-2 Omicron BA.2 Infection in Taiwan

Jainn Jim Lin*, Yi Fang Tu, Shyi Jou Chen, Yung Ting Kuo, Mei Jy Jeng, Mary Hsin-Ju Ko, Cheng Hsun Chiu

*此作品的通信作者

研究成果: Article同行評審

12 引文 斯高帕斯(Scopus)

摘要

Acute fulminant cerebral edema in children following SARS-CoV-2 infection has been rarely reported. Such patients frequently demonstrate rapid progression and are usually fatal. In this retrospective study, we describe the detailed clinical, laboratory, and neuroimaging features of six fatal cases in Taiwan. All patients had shock initially, five showed rapid progression to multiorgan failure and disseminated intravascular coagulation, and three developed acute respiratory distress syndromes. The inflammatory biomarkers in the first 3 days, including interleukin 6, ferritin, lactate dehydrogenase, and D-dimer, showed significant elevation in all cases. The hyperinflammatory response may play a role in the pathophysiology.

原文English
頁(從 - 到)99-103
頁數5
期刊Journal of the Pediatric Infectious Diseases Society
12
發行號2
DOIs
出版狀態Published - 1 2月 2023

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