Fabrication of silicon dioxide nano array for bio-mimicking of molecular interactions

Hui Hsin Lu, Chii Wann Lin*, Tzu-Chien Hsiao, Chih Kung Lee, Su Ming Hsu

*此作品的通信作者

研究成果: Conference contribution同行評審

摘要

We employed atomic force microscopy (AFM) with bias control to fabricate oxided nanopatterns on silicon surface with feature size down to 50nm. The relationship of silicon dioxide nanopatterns against humidity was studied and then the optimal parameter was used to make oxide nanoarry for interaction of biotin and streptavidin. The scanning function of AFM was utilized to verify the different height of biomolecules. According to our experimental results, using nano biochip of silicon dioxide can decrease the monitoring scale to nanometer and can be the nano-platform for monitoring the behavior of biomolecular interaction. We anticipate mimicking the correlation of single molecular behavior and an array of biomolecular behavior to understand the coincidence of them.

原文English
主出版物標題Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications V
DOIs
出版狀態Published - 2008
事件Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications V - San Jose, CA, United States
持續時間: 21 1月 200823 1月 2008

出版系列

名字Progress in Biomedical Optics and Imaging - Proceedings of SPIE
6865
ISSN(列印)1605-7422

Conference

ConferenceNanoscale Imaging, Sensing, and Actuation for Biomedical Applications V
國家/地區United States
城市San Jose, CA
期間21/01/0823/01/08

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