@inproceedings{5d70866c85d345bda387d1020aec772e,
title = "Fabrication of silicon dioxide nano array for bio-mimicking of molecular interactions",
abstract = "We employed atomic force microscopy (AFM) with bias control to fabricate oxided nanopatterns on silicon surface with feature size down to 50nm. The relationship of silicon dioxide nanopatterns against humidity was studied and then the optimal parameter was used to make oxide nanoarry for interaction of biotin and streptavidin. The scanning function of AFM was utilized to verify the different height of biomolecules. According to our experimental results, using nano biochip of silicon dioxide can decrease the monitoring scale to nanometer and can be the nano-platform for monitoring the behavior of biomolecular interaction. We anticipate mimicking the correlation of single molecular behavior and an array of biomolecular behavior to understand the coincidence of them.",
keywords = "Electrochemical atomic force microscopy, Nano biochip, Silicon dioxide nanopatterns",
author = "Lu, {Hui Hsin} and Lin, {Chii Wann} and Tzu-Chien Hsiao and Lee, {Chih Kung} and Hsu, {Su Ming}",
year = "2008",
month = apr,
day = "21",
doi = "10.1117/12.762919",
language = "English",
isbn = "9780819470409",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications V",
note = "Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications V ; Conference date: 21-01-2008 Through 23-01-2008",
}