@inproceedings{7af8b4cdb5a547df844213cb2af5fb42,
title = "Fabrication of PEG hydrogel microstructures in microfluidic system for multicellular spheroid formation, culturing and analysis",
abstract = "This study presents a novel microfluidic device for 3-dimension cell culturing and analysis. Through defining the exposure to ultra-violet light by a photomask, localized photopolymerization of poly (ethylene glycol) diacrylate hydrogels form biocompatible and permselective microstructures within a microfluidic device. The designed geometry of microstructures allowed cells to be trapped into structures and to form spheroids in situ. Subsequent analysis and long-term three-dimension cell culture can achieve within the same device. This technique may apply as a microscale bioreactor or a platform for spheroid-based drug screening and study.",
keywords = "Drug screening, Microfluidic systems, Microscale bioreactor, Multicellular spheroids, Photoresponsive hydrogel",
author = "Fu, {Chien Yu} and Tseng, {Sheng Yang} and Yang, {Shih Mo} and Long Hsu and Liu, {Cheng Hsien} and Chang, {Hwan You}",
year = "2011",
month = jun,
day = "13",
language = "English",
isbn = "9781439871386",
series = "Technical Proceedings of the 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011",
pages = "98--100",
booktitle = "Technical Proceedings of the 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011",
note = "Nanotechnology 2011: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011 ; Conference date: 13-06-2011 Through 16-06-2011",
}