This paper reports a method to fabricate biodegradable, adhesive and soft tissue-compliant microelectrode arrays (MEAs). MEAs composed of polylactic acid (PLA) biodegradable insulation layers and Pt/PLA hybrid electrodes can be fabricated in a batch by photolithography with a tunable photoresist/developer composition. The coordinated sacrificial layer dissolution and interfacial adhesion driven by an adhesive hydrogel enable directly transfer printing Pt-PLA MEAs stacks. This integrated process will allow, for first time, the batch production of implanted hydrogel MEAs composed of metal/organic composites as conformal electrodes and fully biodegradable insulation layers to show significantly lower impedance (0.1-2.5 kΩ) at 1 kHz as compared with those reported from most literatures. This device enables the success of both in-vivo site-specific neural stimulation and recording.