Extra-major salivary gland pleomorphic adenoma of the head and neck: A 10-year experience and review of the literature

Yen Ling Kuo, Tzong Yang Tu*, Chia Fan Chang, Wing Yin Li, Shyue Yih Chang, An Suey Shiao, Pen Yuan Chu, Kee Tak Chan, Shyh Kuan Tai, Yi Fen Wang, Shu Ching Kao, Shou Yen Kao, Wen Liang Lo, Cheng Hsien Wu, Wen Hu Shu, Shu Ma, Tien Hsiang Wang

*此作品的通信作者

研究成果: Article同行評審

36 引文 斯高帕斯(Scopus)

摘要

Pleomorphic adenomas, or benign mixed tumors, make up 65% of all salivary gland tumors. They also can be found as solid tumors in other parts of the head and neck region, such as the auditory canal, the eyelids, and the orbital area. In this study, we investigated extra-major salivary gland pleomorphic adenomas of the head and neck region retrospectively at a tertiary care center. Between March 1998 and June 2009, 37 patients underwent primary surgery for extra-major salivary gland pleomorphic adenoma of the head and neck. The duration of symptoms, radiographic findings, operative procedures, and pathologic findings were documented. Of the 37 patients enrolled, 22 were male and 15 were female, with a median age of 57 years. Tumors were found in the soft palate, hard palate, nasopharynx, orbital area, trachea, buccal mucosa, cheek, nasal septum, upper lip, lower eyelid, and external auditory canal. Cellular variant of the pleomorphic adenoma was found in four patients, while the remaining patients presented with the classic variant. No myxoid subgroup was noted in our study. Carcinoma ex pleomorphic adenoma was observed only in one patient for whom radical surgery was performed. Twenty-eight patients (76%) had long-term follow-ups, with the average follow-up period being 4.5 years. Local recurrence was observed in three patients, and they underwent revision surgery during the follow-up period. Our results indicate that extra-major salivary gland pleomorphic adenomas are most commonly found in the soft palate. Wide excision was the treatment of choice, although its efficacy might be compromised with cosmetics and functional structures of the head and neck. Therefore, long-term follow-up of patients is necessary.

原文English
頁(從 - 到)1035-1040
頁數6
期刊European Archives of Oto-Rhino-Laryngology
268
發行號7
DOIs
出版狀態Published - 7月 2011

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