摘要
Current imaging tools are insufficiently sensitive to the early diagnosis of esophageal squamous cell carcinoma (ESCC). The application of polarization-sensitive optical coherence tomography (PS-OCT) to detect tumor-stroma interaction is an interesting issue in cancer diagnosis. In this translational study, we found that en-face PS-OCT effectively characterizes protruding, flat, and depressive type ESCC regardless of animal or human specimens. In addition, the tumor contour and margin could also be drawn and determined on a broad en-face view. The determined tumor margin could be in the proximity of 2 mm to the actual tumor margin, which was proved directly using histology.
原文 | English |
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頁(從 - 到) | 4773-4786 |
頁數 | 14 |
期刊 | Biomedical Optics Express |
卷 | 13 |
發行號 | 9 |
DOIs | |
出版狀態 | Published - 1 9月 2022 |