Emerging roles for myosin II and cytoplasmic dynein in migrating neurons and growth cones

Richard B. Vallee*, Garrett E. Seale, Jin Wu Tsai

*此作品的通信作者

研究成果: Review article同行評審

113 引文 斯高帕斯(Scopus)

摘要

Motor proteins are involved in a wide range of cellular and subcellular movements. Recent studies have implicated two motor proteins in particular, myosin II and cytoplasmic dynein, in diverse aspects of cell migration. This review focuses on emerging roles for these proteins in the nervous system, with particular emphasis on migrating neurons and neuronal growth cones. The former cells exhibit unusual features of centrosome and nuclear movement, whereas growth cones offer an opportunity to evaluate motor protein function in a region of cytoplasm free of these organelles.

原文English
頁(從 - 到)347-355
頁數9
期刊Trends in Cell Biology
19
發行號7
DOIs
出版狀態Published - 7月 2009

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