摘要
We report a protocol for alkene hydroxyalkenylation. Using a persulfate anion as a one-electron-oxidation reagent and 1,2-bis(phenylsulfonyl)ethylene as a radical acceptor in the presence of water, alkenes were converted into the corresponding 1-phenylsulfonyl-4-hydroxyalkenes in good to high yields. The hydroxyalkenylation process involves the nucleophilic hydroxylation of alkene radical cations to give β-hydroxyalkyl radicals, which, after a radical addition/β-elimination sequence, provide the products. We also report a photocatalytic protocol for alkoxyalkenylation.
原文 | English |
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文章編號 | e202311807 |
期刊 | Angewandte Chemie - International Edition |
卷 | 62 |
發行號 | 49 |
DOIs | |
出版狀態 | Published - 4 12月 2023 |