Effects of cisapride on colonic transit in patients with progressive systemic sclerosis

S. J. Wang; J. L. Lan; J. L. Lan; D. Y. Chen; Y. H. Chen; T. Y. Hsieh; W. Y. Lin

doi:10.1007/s100670200072

Effects of cisapride on colonic transit in patients with progressive systemic sclerosis

S. J. Wang^*, J. L. Lan, J. L. Lan, D. Y. Chen, Y. H. Chen, T. Y. Hsieh, W. Y. Lin

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摘要

Progressive systemic sclerosis (PSS) may involve any portion of the gastrointestinal tract, including the colon. Constipation is common in patients with PSS. Cisapride, a benzamide derivative, is a potentially useful agent in the treatment of chronic idiopathic constipation. The effect of cisapride on colonic transit was evaluated in 16 PSS patients by a radionuclide colonic transit method. Each patient received cisapride orally three times a day for a week. The results showed acceleration in colonic transit in response to cisapride. We conclude that cisapride is effective in the treatment of constipation in patients with PSS.

原文	English
頁（從 - 到）	271-274
頁數	4
期刊	Clinical Rheumatology
卷	21
發行號	4
DOIs	https://doi.org/10.1007/s100670200072
出版狀態	Published - 8月 2002

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title = "Effects of cisapride on colonic transit in patients with progressive systemic sclerosis",

abstract = "Progressive systemic sclerosis (PSS) may involve any portion of the gastrointestinal tract, including the colon. Constipation is common in patients with PSS. Cisapride, a benzamide derivative, is a potentially useful agent in the treatment of chronic idiopathic constipation. The effect of cisapride on colonic transit was evaluated in 16 PSS patients by a radionuclide colonic transit method. Each patient received cisapride orally three times a day for a week. The results showed acceleration in colonic transit in response to cisapride. We conclude that cisapride is effective in the treatment of constipation in patients with PSS.",

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AU - Lan, J. L.

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AU - Hsieh, T. Y.

AU - Lin, W. Y.

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N2 - Progressive systemic sclerosis (PSS) may involve any portion of the gastrointestinal tract, including the colon. Constipation is common in patients with PSS. Cisapride, a benzamide derivative, is a potentially useful agent in the treatment of chronic idiopathic constipation. The effect of cisapride on colonic transit was evaluated in 16 PSS patients by a radionuclide colonic transit method. Each patient received cisapride orally three times a day for a week. The results showed acceleration in colonic transit in response to cisapride. We conclude that cisapride is effective in the treatment of constipation in patients with PSS.

AB - Progressive systemic sclerosis (PSS) may involve any portion of the gastrointestinal tract, including the colon. Constipation is common in patients with PSS. Cisapride, a benzamide derivative, is a potentially useful agent in the treatment of chronic idiopathic constipation. The effect of cisapride on colonic transit was evaluated in 16 PSS patients by a radionuclide colonic transit method. Each patient received cisapride orally three times a day for a week. The results showed acceleration in colonic transit in response to cisapride. We conclude that cisapride is effective in the treatment of constipation in patients with PSS.

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ER -

Effects of cisapride on colonic transit in patients with progressive systemic sclerosis

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