Dynamic attachment of HepG2 in fractal microchannels

Lung Jieh Yang*, Jia Chi Liang, Cheng Yang Liu, Hsieh Cheng Han

*此作品的通信作者

研究成果: Conference contribution同行評審

摘要

Dynamic filling experiments using HepG2 tumor cells are performed for observing the attachment behavior novelly in fractal microchannels. A PDMS microchannel mimicking the capillary blood vessel with fractal configuration is fabricated by the gelatin salt-out technique and the PDMS soft lithography. The fabrication of this low-toxicity fractal PDMS microchannel is firstly addressed herein. Using this PDMS microchannel, PBS with living HepG2 tumor cells are filled through. The cell attachment areas in the PDMS microchannel have been recorded dynamically with 10 min interval continuously for 2 hours. The result show that 2 hour is not enough for the permanent cell attachment of HepG2 in this fractal PDMS microchannel.

原文English
主出版物標題9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014
發行者Institute of Electrical and Electronics Engineers Inc.
頁面51-54
頁數4
ISBN(電子)9781479947270
DOIs
出版狀態Published - 23 9月 2014
事件9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014 - Waikiki Beach, United States
持續時間: 13 4月 201416 4月 2014

出版系列

名字9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014

Conference

Conference9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014
國家/地區United States
城市Waikiki Beach
期間13/04/1416/04/14

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