Dry eye in the beaver dam offspring study: Prevalence, risk factors, and health-related quality of life

Adam J. Paulsen*, Karen J. Cruickshanks, Mary E. Fischer, Guan-Hua Huang, Barbara E.K. Klein, Ronald Klein, Dayna S. Dalton

*此作品的通信作者

研究成果: Article同行評審

269 引文 斯高帕斯(Scopus)

摘要

Purpose To estimate dry eye prevalence in the Beaver Dam Offspring Study (BOSS), including a young adult population, and investigate associated risk factors and impact on health-related quality of life. Design Cohort study. Methods The BOSS (2005-2008) is a study of aging in the adult offspring of the population-based Epidemiology of Hearing Loss Study cohort. Questionnaire data on health history, medication use, risk factors, and quality of life were available for 3275 participants. Dry eye was determined by self-report of frequency of symptoms and the intensity of those symptoms. Associations between dry eye and risk factors were analyzed using logistic regression. Results The prevalence of dry eye in the BOSS was 14.5%: 17.9% of women and 10.5% of men. In a multivariate model, statistically significant associations were found with female sex (odds ratio [OR], 1.68; 95% confidence interval [CI], 1.33-2.11), current contact lens use (OR, 2.01; 95% CI, 1.53-2.64), allergies (OR, 1.59; 95% CI, 1.22-2.08), arthritis (OR, 1.44; 95% CI, 1.12-1.85), thyroid disease (OR, 1.43; 95% CI, 1.02-1.99), antihistamine use (OR, 1.54; 95% CI, 1.18-2.02), and steroid use (OR, 1.54; 95% CI, 1.16-2.06). Dry eye was also associated with lower scores on the Medical Outcomes Study Short Form 36 (β = -3.9, P <.0001) as well as on the National Eye Institute 25-Item Visual Function Questionnaire (NEI VFQ-25) (β = -3.4, P <.0001) when controlling for age, sex, and comorbid conditions. Conclusions The prevalence of dry eye and its associated risk factors in the BOSS were similar to previous studies. In this study, dry eye was associated with lower quality of life on a health-related quality-of-life instrument and the vision-specific NEI VFQ-25.

原文English
頁(從 - 到)799-806
頁數8
期刊American Journal of Ophthalmology
157
發行號4
DOIs
出版狀態Published - 4月 2014

指紋

深入研究「Dry eye in the beaver dam offspring study: Prevalence, risk factors, and health-related quality of life」主題。共同形成了獨特的指紋。

引用此