Dose evaluation of a blood irradiator using Monte Carlo simulation and MAGAT gel dosimeter

Tian Yu Shih, Yan Lin Liu, Ho Hsing Chen, Jay Wu*

*此作品的通信作者

研究成果: Review article同行評審

4 引文 斯高帕斯(Scopus)

摘要

Blood irradiators are frequently used to irradiate blood products to decrease the occurrence of the graft versus host disease. The dose distribution within the irradiation volume is affected by the source and sample geometry. Understanding the dose distribution is therefore necessary. In this study, the Monte Carlo technique was used to construct the geometry of the blood irradiator, and simulate the Cs-137 exposure to the sample. Absorbed doses were tallied in different distances from the central axis, and compared with the results obtained by the MAGAT gel and gafchromic film. In the x-axis, the dose outside the irradiation cavity was higher than that at the center. The average dose difference measured between the gel dosimeter and the Monte Carlo simulation was 4.58%, while that between the film and the Monte Carlo simulation was 2.8%. In the z-axis, the dose at the upper and lower ends was lower than those at the center. The maximum difference between the film and the Monte Carlo simulation was 1.05 Gy, while it was 3.46 Gy between the gel dosimeter and the Monte Carlo simulation. The uniformity of the dose distribution in the irradiation volume can be evaluated using the gel dosimeter and Monte Carlo method to ensure that blood products can achieve the accurate dose delivery.

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