DNA translocation dynamics through short nanochannels under asymmetric pulsed electric field

Cherry Gupta, Wei Ching Liao, Daniel Gallego-Perez, Carlos E. Castro, L. James Lee*

*此作品的通信作者

研究成果: Conference contribution同行評審

摘要

We present our work on DNA dynamics in short polymeric nanochannels under pulsed electric fields and simulate their behavior using Brownian Dynamics. Our results show that the time taken by a DNA molecule to traverse a short nanochannel varies non-linearly with the applied voltage and depends on the length of the translocating DNA. We exploit this to separate two DNA of different lengths by applying an asymmetric electrical pulse.

原文English
主出版物標題17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
發行者Chemical and Biological Microsystems Society
頁面817-819
頁數3
ISBN(列印)9781632666246
出版狀態Published - 2013
事件17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
持續時間: 27 10月 201331 10月 2013

出版系列

名字17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
2

Conference

Conference17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
國家/地區Germany
城市Freiburg
期間27/10/1331/10/13

指紋

深入研究「DNA translocation dynamics through short nanochannels under asymmetric pulsed electric field」主題。共同形成了獨特的指紋。

引用此