Directly thiolated modification onto the surface of detonation nanodiamonds

Ming Hua Hsu*, Hong Chuang, Fong Yu Cheng, Ying Pei Huang, Chien Chung Han, Jiun Yu Chen, Su Chin Huang, Jen Kun Chen, Dian Syue Wu, Hsueh Liang Chu, Chia-Ching Chang


研究成果: Article同行評審

32 引文 斯高帕斯(Scopus)


An efficient method for modifying the surface of detonation nanodiamonds (5 and 100 nm) with thiol groups (-SH) by using an organic chemistry strategy is presented herein. Thiolated nanodiamonds were characterized by spectroscopic techniques, and the atomic percentage of sulfur was analyzed by elemental analysis and X-ray photoelectron spectroscopy. The conjugation between thiolated nanodiamonds and gold nanoparticles was elucidated by transmission electron microscopy and UV-vis spectrometry. Moreover, the material did not show significant cytotoxicity to the human lung carcinoma cell line and may prospectively be applied in bioconjugated technology. The new method that we elucidated may significantly improve the approach to surface modification of detonation nanodiamonds and build up a new platform for the application of nanodiamonds.

頁(從 - 到)7198-7203
期刊ACS Applied Materials and Interfaces
出版狀態Published - 28 5月 2014


深入研究「Directly thiolated modification onto the surface of detonation nanodiamonds」主題。共同形成了獨特的指紋。