TY - JOUR
T1 - Diagnostic performance of a stand-alone central blood pressure monitor
T2 - Application of central blood pressure in the diagnosis of high blood pressure
AU - Cheng, Hao Min
AU - Sung, Shih Hsien
AU - Chuang, Shao Yuan
AU - Pearson, Alan
AU - Tufanaru, Catalin
AU - White, Sarahlouise
AU - Yu, Wen Chung
AU - Chen, Chen Huan
PY - 2014/3
Y1 - 2014/3
N2 - BACKGROUNDOscillometric central blood pressure (CBP) monitors have emerged as a new technology for blood pressure (BP) measurements. With a newly proposed diagnostic threshold for CBP, we investigated the diagnostic performance of a novel CBP monitor.METHODSWe recruited a consecutive series of 138 subjects (aged 30-93 years) without previous use of antihypertensive agents for simultaneous invasive and noninvasive measurements of BP in a catheterization laboratory. With the cutoff (CBP ≥130/90mm Hg) for high blood pressure (HBP), the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the novel CBP monitor were calculated with reference to the measured CBP. In comparison, the diagnostic performance of the conventional cuff BP was also evaluated.RESULTSThe noninvasive CBP for detecting HBP in a sample with a prevalence of 52% showed a sensitivity of 93% (95% confidence interval (CI) = 91-95), specificity of 95% (95% CI = 94-97), PPV of 96% (95% CI = 94-97), and NPV of 93% (95% CI = 90-95). In contrast, with cuff BP and the traditional HBP criterion (cuff BP ≥140/90mm Hg), the sensitivity, specificity, PPV, and NPV were 49% (95% CI = 44-53), 94% (95% CI = 92-96), 90% (95% CI = 86-93), and 63% (95% CI 59-66), respectively.CONCLUSIONSA stand-alone oscillometric CBP monitor may provide CBP values with acceptable diagnostic accuracy. However, with reference to invasively measured CBP, cuff BP had low sensitivity and NPV, which could render possible management inaccessible to a considerable proportion of HBP patients, who may be identifiable through noninvasive CBP measurements from the CBP monitor.
AB - BACKGROUNDOscillometric central blood pressure (CBP) monitors have emerged as a new technology for blood pressure (BP) measurements. With a newly proposed diagnostic threshold for CBP, we investigated the diagnostic performance of a novel CBP monitor.METHODSWe recruited a consecutive series of 138 subjects (aged 30-93 years) without previous use of antihypertensive agents for simultaneous invasive and noninvasive measurements of BP in a catheterization laboratory. With the cutoff (CBP ≥130/90mm Hg) for high blood pressure (HBP), the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the novel CBP monitor were calculated with reference to the measured CBP. In comparison, the diagnostic performance of the conventional cuff BP was also evaluated.RESULTSThe noninvasive CBP for detecting HBP in a sample with a prevalence of 52% showed a sensitivity of 93% (95% confidence interval (CI) = 91-95), specificity of 95% (95% CI = 94-97), PPV of 96% (95% CI = 94-97), and NPV of 93% (95% CI = 90-95). In contrast, with cuff BP and the traditional HBP criterion (cuff BP ≥140/90mm Hg), the sensitivity, specificity, PPV, and NPV were 49% (95% CI = 44-53), 94% (95% CI = 92-96), 90% (95% CI = 86-93), and 63% (95% CI 59-66), respectively.CONCLUSIONSA stand-alone oscillometric CBP monitor may provide CBP values with acceptable diagnostic accuracy. However, with reference to invasively measured CBP, cuff BP had low sensitivity and NPV, which could render possible management inaccessible to a considerable proportion of HBP patients, who may be identifiable through noninvasive CBP measurements from the CBP monitor.
KW - Microlife WatchBP Office Central
KW - blood pressure
KW - central blood pressure
KW - diagnostic accuracy
KW - hypertension
KW - oscillometric signals
KW - pulse volume plethysmography
KW - sensitivity and specificity
KW - sphygmomanometer
UR - http://www.scopus.com/inward/record.url?scp=84894228427&partnerID=8YFLogxK
U2 - 10.1093/ajh/hpt282
DO - 10.1093/ajh/hpt282
M3 - Article
C2 - 24473253
AN - SCOPUS:84894228427
SN - 0895-7061
VL - 27
SP - 382
EP - 391
JO - American Journal of Hypertension
JF - American Journal of Hypertension
IS - 3
ER -