Cortical complexity analysis of patients with bipolar disorder using three-dimensional gyrification index

Yuan Lin Liao, Yung Nien Sun, Jen Chuen Hsieh, Tung Ping Su, Wan Yuo Guo, Yu Te Wu*

*此作品的通信作者

研究成果: Conference contribution同行評審

4 引文 斯高帕斯(Scopus)

摘要

Bipolar disorder (BD) is a common affective disorder. In morphometric brain imaging studies, BD subjects have atrophic gray matter, especially in the prefrontal area. These structural abnormalities could involve the change of cortical shape. Gyrification index (GI) is a useful metric to measure the degree of cortical complexity. This work aims to compare the cortical development between bipolar patients and healthy controls using GI. No significant difference was detected between two groups. However, we found asymmetry pattern of cortical complexity was increased in limbic lobe on bipolar patients. Significant negative correlation was also observed between rating scores and asymmetry coefficients in frontal lobe.

原文English
主出版物標題Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
頁面3933-3936
頁數4
出版狀態Published - 8月 2008
事件30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada
持續時間: 20 8月 200825 8月 2008

出版系列

名字Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"

Conference

Conference30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
國家/地區Canada
城市Vancouver, BC
期間20/08/0825/08/08

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