Corrosion resistance and biocompatibility of anodized titanium surface with Tio ₂-network layer

In this study, we studied the corrosion resistance, bacteria adhesion, blood coagulation, and cell adhesion of a nano-scale titanium dioxide (TiO ₂) layer on Ti surface for dental implant application. A TiO ₂ nano-network surface layer with an average lateral pore size of 65 and 94 nm and oxide thickness of 180 to 350 nm could be rapidly produced on Ti surface using a simple electrochemical anodization treatment, applying different anodic currents to Ti surface. Increasing the applied anodic current led to an increase in the pore size and thickness of network layer. The presence of nano-scale TiO ₂ network surface layer significantly increased the corrosion resistance in artificial saliva with and without fluoride ions, decreased the bacteria adhesion, enhanced the fresh whole blood coagulation, and improved the human mesenchymal stem cell adhesion on Ti surface for dental implant application. The evaluation of the detailed mechanisms for improving the corrosion resistance, bacteria adhesion, blood coagulation, and cell adhesion of the nano-scale TiO ₂ network surface layer are now in progress.