Corrigendum: A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction (Front. Immunol., (2020), 11, (607564), 10.3389/fimmu.2020.607564)

Chun Hsien Wu, Chin Heng Gan, Lan Hui Li, Jen Che Chang, Shin Tai Chen, Mridula P. Menon, Shu Meng Cheng, Shih Ping Yang, Chen Lung Ho, Oleg V. Chernikov, Chi Hung Lin, Yulin Lam*, Kuo Feng Hua

*此作品的通信作者

研究成果: Comment/debate

摘要

In the original article, there was a mistake in Figures 5E and 8E as published. We found a mismatch between the Western blot images (p-JNK1/2) in comparison to the labeling in Figures 5E. Regarding the effect of F240B on LPS-induced phosphorylation of ERK1/2, p38 and JNK1/2, we tested two time-course studies: (A) condition was LPS treatment for 0, 10, 20, 30 min (total eight groups), (A) condition was LPS treatment for 0, 10, 20, 30, 60 min (total ten groups). In the Figures 5E of the original manuscript, we used (A) condition for ERK1/2, p38; however, we used (B) condition for JNK. In addition, in Figures 8E of the original manuscript, the Western blot image of input NLRP3 included a non-specific band (far left band), making it looks like a mismatch between input NLRP3 and input PKR. The corrected Figures 5E and 8E appear below. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

原文English
文章編號738591
期刊Frontiers in Immunology
12
DOIs
出版狀態Published - 15 12月 2021

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