Copper complex of a pyridine-modified poly(amidoamine) dendrimer as a chemical nuclease: Synthetic and catalytic study

Chai Lin Kao*, Yi Hsuan Tang, Yen Chung Lin, Li Ting Chiu, Hui Ting Chen, Sodio C.N. Hsu, Kuang Chan Hsieh, Chi Yu Lu, Yeh Long Chen

*此作品的通信作者

研究成果: Article同行評審

17 引文 斯高帕斯(Scopus)

摘要

[CuY((G:2-6)-dendri-PAMAM-(Py)n)]2Y+ complexes (3) were prepared, and their ability to generate oxygen radical anions was investigated. The maximum catalytic efficiency (k'cat/KM) was found to be 0.32 min-1.μM-1, and a positive dendritic effect was observed. The saturated kinetics revealed that the improved catalytic efficiency resulted from an enhanced binding affinity toward molecular oxygen.

原文English
頁(從 - 到)273-276
頁數4
期刊Nanomedicine: Nanotechnology, Biology, and Medicine
7
發行號3
DOIs
出版狀態Published - 6月 2011

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