摘要
Synergistic control over the SH2 transition states of hydrogen abstraction exploiting polar and steric effects provides a promising cooperative strategy for site-selective C(sp3)−H functionalization using decatungstate anion photocatalysis. By using this photocatalytic approach, the C−H bonds of substituted lactones and cyclic ketones were functionalized selectively. In the remarkable case of 2-isoamyl 4-tert-butyl cyclohexanone (1 t) bearing five methyl, five methylene, and three methine C−H bonds, one methine C−H bond in the isoamyl tether was selectively functionalized.
原文 | English |
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頁(從 - 到) | 8615-8618 |
頁數 | 4 |
期刊 | Chemistry - A European Journal |
卷 | 23 |
發行號 | 36 |
DOIs | |
出版狀態 | Published - 27 6月 2017 |