TY - JOUR
T1 - Composition of phenolic compounds and antioxidant attributes of Cyclea gracillima Diels extracts
AU - Lin, Jau Tien
AU - Liu, Shih Chuan
AU - Kuo, Li Chun
AU - Yang, Deng Jye
N1 - Publisher Copyright:
© 2017
PY - 2018/1
Y1 - 2018/1
N2 - Cyclea gracillima Diels is a Taiwanese native medicinal herb. However, there are currently few relevant reports on its biochemical activity. In this study, the antioxidant attributes of the ethanol and hot water extracts of this herb were assayed using in vitro models, including the following: 2,2-diphenyl-1-(2,4,6-trinitrophenyl)-hydrazyl radical scavenging, Trolox equivalent antioxidant capacity, reducing power, and chelating ferrous ions. The following biochemical models were also assayed: inhibition of human low density lipoprotein oxidation, inhibition of human erythrocyte hemolysis, and scavenging oxygen radicals in human blood. The composition and content of flavonoids and phenolic acids in these extracts were also analyzed. The results showed that these extracts with high polyphenol levels presented remarkable antioxidant effects in all assays, especially when extracted with ethanol. Six phenolic acids (mainly ferulic acid, sinapic acid, and syringic acid) and 12 flavonoids (mainly narigenin, myricetin, naringin, and apigenin) were found in these extracts.
AB - Cyclea gracillima Diels is a Taiwanese native medicinal herb. However, there are currently few relevant reports on its biochemical activity. In this study, the antioxidant attributes of the ethanol and hot water extracts of this herb were assayed using in vitro models, including the following: 2,2-diphenyl-1-(2,4,6-trinitrophenyl)-hydrazyl radical scavenging, Trolox equivalent antioxidant capacity, reducing power, and chelating ferrous ions. The following biochemical models were also assayed: inhibition of human low density lipoprotein oxidation, inhibition of human erythrocyte hemolysis, and scavenging oxygen radicals in human blood. The composition and content of flavonoids and phenolic acids in these extracts were also analyzed. The results showed that these extracts with high polyphenol levels presented remarkable antioxidant effects in all assays, especially when extracted with ethanol. Six phenolic acids (mainly ferulic acid, sinapic acid, and syringic acid) and 12 flavonoids (mainly narigenin, myricetin, naringin, and apigenin) were found in these extracts.
KW - antioxidant
KW - Cyclea gracillima Diels
KW - flavonoid
KW - phenol
KW - phenolic acid
UR - http://www.scopus.com/inward/record.url?scp=85018961386&partnerID=8YFLogxK
U2 - 10.1016/j.jfda.2017.03.004
DO - 10.1016/j.jfda.2017.03.004
M3 - Article
C2 - 29389555
AN - SCOPUS:85018961386
SN - 1021-9498
VL - 26
SP - 193
EP - 200
JO - Journal of Food and Drug Analysis
JF - Journal of Food and Drug Analysis
IS - 1
ER -