Colonic transit disorders in systemic sclerosis

S. J. Wang; J. L. Lan; D. Y. Chen; Y. H. Chen; T. Y. Hsieh; W. Y. Lin

doi:10.1007/s100670170038

Colonic transit disorders in systemic sclerosis

S. J. Wang^*, J. L. Lan, D. Y. Chen, Y. H. Chen, T. Y. Hsieh, W. Y. Lin

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摘要

Systemic sclerosis (SS) alters smooth muscle function throughout the gastrointestinal tract, the oesophagus being the segment most often involved. Involvement of the colon, though less common, may lead to life-threatening complications. We studied 23 unselected patients with SS and 20 age-matched healthy controls using radionuclide colon transit studies. The geometric centre (GC) at 4 and 24 hours was used to summarise overall transit in the colon. In patients with SS, colon transit was delayed (GC₄: 0.39 ± 0.36 vs 0.85 ± 0.45; P=0.001) (GC₂₄: 1.68 ± 0.9 vs 2.58 ± 1.08; P=0.006). These findings suggest that delayed colon transit is common in patients with SS.

原文	English
頁（從 - 到）	251-254
頁數	4
期刊	Clinical Rheumatology
卷	20
發行號	4
DOIs	https://doi.org/10.1007/s100670170038
出版狀態	Published - 2001

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title = "Colonic transit disorders in systemic sclerosis",

abstract = "Systemic sclerosis (SS) alters smooth muscle function throughout the gastrointestinal tract, the oesophagus being the segment most often involved. Involvement of the colon, though less common, may lead to life-threatening complications. We studied 23 unselected patients with SS and 20 age-matched healthy controls using radionuclide colon transit studies. The geometric centre (GC) at 4 and 24 hours was used to summarise overall transit in the colon. In patients with SS, colon transit was delayed (GC4: 0.39 ± 0.36 vs 0.85 ± 0.45; P=0.001) (GC24: 1.68 ± 0.9 vs 2.58 ± 1.08; P=0.006). These findings suggest that delayed colon transit is common in patients with SS.",

keywords = "Charcoal, Colon, Scintigraphy, Systemic sclerosis",

author = "Wang, {S. J.} and Lan, {J. L.} and Chen, {D. Y.} and Chen, {Y. H.} and Hsieh, {T. Y.} and Lin, {W. Y.}",

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T1 - Colonic transit disorders in systemic sclerosis

AU - Wang, S. J.

AU - Lan, J. L.

AU - Chen, D. Y.

AU - Chen, Y. H.

AU - Hsieh, T. Y.

AU - Lin, W. Y.

PY - 2001

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N2 - Systemic sclerosis (SS) alters smooth muscle function throughout the gastrointestinal tract, the oesophagus being the segment most often involved. Involvement of the colon, though less common, may lead to life-threatening complications. We studied 23 unselected patients with SS and 20 age-matched healthy controls using radionuclide colon transit studies. The geometric centre (GC) at 4 and 24 hours was used to summarise overall transit in the colon. In patients with SS, colon transit was delayed (GC4: 0.39 ± 0.36 vs 0.85 ± 0.45; P=0.001) (GC24: 1.68 ± 0.9 vs 2.58 ± 1.08; P=0.006). These findings suggest that delayed colon transit is common in patients with SS.

AB - Systemic sclerosis (SS) alters smooth muscle function throughout the gastrointestinal tract, the oesophagus being the segment most often involved. Involvement of the colon, though less common, may lead to life-threatening complications. We studied 23 unselected patients with SS and 20 age-matched healthy controls using radionuclide colon transit studies. The geometric centre (GC) at 4 and 24 hours was used to summarise overall transit in the colon. In patients with SS, colon transit was delayed (GC4: 0.39 ± 0.36 vs 0.85 ± 0.45; P=0.001) (GC24: 1.68 ± 0.9 vs 2.58 ± 1.08; P=0.006). These findings suggest that delayed colon transit is common in patients with SS.

KW - Charcoal

KW - Colon

KW - Scintigraphy

KW - Systemic sclerosis

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DO - 10.1007/s100670170038

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JO - Clinical Rheumatology

JF - Clinical Rheumatology

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Colonic transit disorders in systemic sclerosis

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