Cholesterol-3-beta, 5-alpha, 6-beta-triol induced PI₃K-Akt-eNOS-dependent cyclooxygenase-2 expression in endothelial cells

Keyphrases

• Endothelial Cells 100%
• Cholesterol 100%
• Endothelial Nitric Oxide Synthase (eNOS) 100%
• AKT1 100%
• Cyclooxygenase-2 Expression 100%
• Triol 100%
• Cyclooxygenase-2 50%
• Protein Expression 37%
• NF-B 37%
• MRNA Expression 25%
• P38 Mitogen-activated Protein Kinase (p38 MAPK) 25%
• Oxidized Low-density Lipoprotein (ox-LDL) 25%
• Human Umbilical Vein Endothelial Cells (HUVECs) 25%
• L-NAME 12%
• Nitric Oxide Production 12%
• Concentration-dependent 12%
• Phosphorylation 12%
• Gene Expression 12%
• Akt Phosphorylation 12%
• Protein Concentration 12%
• Phosphoinositide 3-kinase (PI3K) 12%
• Prostaglandin E2 12%
• Protein Phosphorylation 12%
• LY294002 12%
• PI3K Inhibitor 12%
• P38 Phosphorylation 12%
• COX-2 Gene 12%
• Regulatory Pathways 12%
• Protein Induction 12%
• PGE2 Production 12%
• Oxysterols 12%

Biochemistry, Genetics and Molecular Biology

• Protein Kinase B 100%
• Cyclooxygenase 100%
• Protein Expression 75%
• Messenger RNA 75%
• Gene Expression 25%
• Protein Phosphorylation 25%
• Nitric Oxide 25%
• LY294002 25%
• Protein Induction 25%
• P38 Mitogen-Activated Protein Kinases 25%
• Oxysterol 25%

Immunology and Microbiology

• Atherosclerosis 100%
• Protein Expression 100%
• Cyclooxygenase 100%
• Umbilical Vein Endothelial Cell 66%
• Gene Expression 33%
• Protein Phosphorylation 33%
• Protein Induction 33%