TY - JOUR
T1 - Cerebral oxygenation during exercise in patients with cardiopulmonary diseases
T2 - A prospective observational study
AU - Tung, Yu Ju
AU - Yen, Yun Shan
AU - Lin, Bor Shyh
AU - Chou, Willy
N1 - Publisher Copyright:
© 2020, Republic of China Society of Cardiology. All rights reserved.
PY - 2020
Y1 - 2020
N2 - Background: The relationship between exercise and cerebral oxygenation has gained increasing attention. However, few studies have investigated the correlation between exercise and cerebral oxygenation in patients with cardiopulmonary diseases. Objectives: To investigate the correlation between exercise and cerebral oxygenation in patients with cardiopulmonary diseases. Methods: Thirty eligible patients with cardiopulmonary diseases underwent incremental cardiopulmonary exercising test (CPET) and near-infrared spectroscopy with both right and left sensors placed at the mid forehead to detect oxygen saturation of cerebral tissue (STO2). Parameters of cerebral oxygenation and exercise intensity were collected and analyzed. Results: The average age of the patients was 51.17 ± 10.21 years and included 23 males and 7 females. The average maximal STO2 of the left and right brain during CPET were 51.850 ± 1.57% and 51.755 ± 1.90%, respectively. Meanwhile, mean oxygen consumption (VO2) while reaching maximal STO2 was 4.42 ± 1.05 metabolic equivalents (METs) over the left brain and 4.34 ± 1.17 METs over the right brain. The exercise intensity upon reaching maximal STO2 was 84.91 ± 11.70% over the left brain and 83.16 ± 14.64% over the right brain. Peak VO2 was significantly correlated to VO2 upon reaching maximal STO2 over the left and right brain (R = 0.805, p < 0.001 and R = 0.739, p < 0.001, respectively). Age was significantly negatively correlated to VO2 upon maximal STO2 over the left and right brain (R =-0.378, p = 0.039 and R =-0.513, p = 0.004, respectively). Conclusions: Cerebral oxygenation increases with higher exercise intensity, and it reaches a maximal STO2 between respiratory compensation point and peak exercise. The higher the peak VO2, the better the VO2 upon reaching maximal STO2.
AB - Background: The relationship between exercise and cerebral oxygenation has gained increasing attention. However, few studies have investigated the correlation between exercise and cerebral oxygenation in patients with cardiopulmonary diseases. Objectives: To investigate the correlation between exercise and cerebral oxygenation in patients with cardiopulmonary diseases. Methods: Thirty eligible patients with cardiopulmonary diseases underwent incremental cardiopulmonary exercising test (CPET) and near-infrared spectroscopy with both right and left sensors placed at the mid forehead to detect oxygen saturation of cerebral tissue (STO2). Parameters of cerebral oxygenation and exercise intensity were collected and analyzed. Results: The average age of the patients was 51.17 ± 10.21 years and included 23 males and 7 females. The average maximal STO2 of the left and right brain during CPET were 51.850 ± 1.57% and 51.755 ± 1.90%, respectively. Meanwhile, mean oxygen consumption (VO2) while reaching maximal STO2 was 4.42 ± 1.05 metabolic equivalents (METs) over the left brain and 4.34 ± 1.17 METs over the right brain. The exercise intensity upon reaching maximal STO2 was 84.91 ± 11.70% over the left brain and 83.16 ± 14.64% over the right brain. Peak VO2 was significantly correlated to VO2 upon reaching maximal STO2 over the left and right brain (R = 0.805, p < 0.001 and R = 0.739, p < 0.001, respectively). Age was significantly negatively correlated to VO2 upon maximal STO2 over the left and right brain (R =-0.378, p = 0.039 and R =-0.513, p = 0.004, respectively). Conclusions: Cerebral oxygenation increases with higher exercise intensity, and it reaches a maximal STO2 between respiratory compensation point and peak exercise. The higher the peak VO2, the better the VO2 upon reaching maximal STO2.
KW - Cardiopulmonary diseases
KW - Cerebral oxygenation
KW - Exercise
UR - http://www.scopus.com/inward/record.url?scp=85096147575&partnerID=8YFLogxK
U2 - 10.6515/ACS.202011_36(6).20200519C
DO - 10.6515/ACS.202011_36(6).20200519C
M3 - Article
AN - SCOPUS:85096147575
SN - 1011-6842
VL - 36
SP - 667
EP - 674
JO - Acta Cardiologica Sinica
JF - Acta Cardiologica Sinica
IS - 6
ER -