Celecoxib induces p53-PUMA pathway for apoptosis in human colorectal cancer cells

Keyphrases

• Apoptosis 100%
• Apoptotic Pathway 100%
• Colorectal Cancer Cells 100%
• P53-dependent Apoptosis 100%
• Celecoxib 100%
• Cytotoxicity 20%
• P53 Protein 20%
• HCT116 Cells 20%
• P53 Wild Type 20%
• Cell Death 10%
• RKO Cells 10%
• Human Colorectal Cancer 10%
• Small Interfering RNA (siRNA) 10%
• Apoptosis Induction 10%
• Non-steroidal Anti-inflammatory Drugs (NSAIDs) 10%
• Mitochondria 10%
• Securin 10%
• Apoptotic Cells 10%
• Cytoplasma 10%
• Apoptosis-related Proteins 10%
• Chemopreventive 10%
• Anticarcinogenic Activity 10%

Immunology and Microbiology

• Cancer Cell 100%
• P53 100%
• P53 Upregulated Modulator of Apoptosis 100%
• Programmed Cell Death 100%
• Serine 20%
• Cytotoxicity 13%
• Wild Type 13%
• Cell Death 6%
• Genetic Transfection 6%
• Mitochondrion 6%

Pharmacology, Toxicology and Pharmaceutical Science

• Protein P53 100%
• Celecoxib 100%
• Colorectal Carcinoma 100%
• PUMA Protein 100%
• Serine 20%
• Cytotoxicity 13%
• Small Interfering RNA 6%
• Non-Steroidal Anti-Inflammatory Drug 6%
• Securin 6%