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Cadmium exposure induces pancreatic β-cell death via a Ca
2+
-triggered JNK/CHOP-related apoptotic signaling pathway
Cheng Chin Huang
, Chun Ying Kuo
, Ching Yao Yang
, Jui Ming Liu
, Ren Jun Hsu
, Kuan I. Lee
, Chin Chuan Su
, Chin Ching Wu
, Ching Ting Lin
, Shing Hwa Liu
, Chun Fa Huang
*
*
此作品的通信作者
醫學系泌尿學科
研究成果
:
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同行評審
39
引文 斯高帕斯(Scopus)
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-triggered JNK/CHOP-related apoptotic signaling pathway」主題。共同形成了獨特的指紋。
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Keyphrases
Ca2+
100%
Cell Death
100%
Apoptotic Pathway
100%
C-Jun N-terminal Kinase
100%
Cadmium Exposure
100%
Pancreatic Cells
100%
C/EBP Homologous Protein
100%
Cadmium
77%
Small Interfering RNA (siRNA)
33%
Cell Toxicity
33%
Insulin Secretion
33%
Kinase Phosphorylation
33%
Apoptosis
22%
Protein Expression
22%
Epidemiological Data
11%
Caspase-3
11%
Intracellular Calcium
11%
Molecular Mechanism
11%
Cell Viability
11%
Type 1 Diabetes Mellitus (T1DM)
11%
Insults
11%
Cell-derived
11%
Hazardous Substances
11%
BAPTA-AM
11%
Apoptotic Cells
11%
Pharmacological Inhibitors
11%
Kinase Activation
11%
Poly(ADP-ribose) Polymerase
11%
Protein Activation
11%
Disease Registry
11%
SP600125
11%
Toxic Substances
11%
Ca2+ Response
11%
Hypodiploidy
11%
Biochemistry, Genetics and Molecular Biology
N-Terminus
100%
Cell Death
100%
Phosphotransferase
100%
Kinase
100%
C-Jun N-Terminal Kinases
100%
Cytotoxicity
37%
Insulin Release
37%
Protein Expression
25%
Small Interfering RNA
25%
Programmed Cell Death
25%
Calcium Cell Level
12%
Caspase 3
12%
Transfection
12%
Cell Viability
12%
Poly ADP Ribose Polymerase
12%
Epidemiological Data
12%
Disease Registry
12%
Pharmacology, Toxicology and Pharmaceutical Science
Calcium Ion
100%
Phosphotransferase
100%
Small Interfering RNA
33%
Cytotoxicity
33%
Caspase 3
11%
Diabetes Mellitus
11%
Protein
11%
Cell Viability
11%
Ethylene Glycol 1,2 Bis(2 Aminophenyl) Ether N,n,n',n' Tetraacetic Acid
11%
Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase
11%
anthra[1,9 Cd]pyrazol 6(2h) One
11%
Toxic Substance
11%
Hazardous Material
11%
Diseases
11%