Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective

Zhenyi An; Wei Chung Chiang; Álvaro F. Fernández; Luis H. Franco; Cong Cong He; Shu Yi Huang; Eunmyong Lee; Yang Liu; Salwa Sebti; Sanae Shoji-Kawata; Shyam Sirasanagandla; Richard C. Wang; Yongjie Wei; Yuting Zhao; Silvia Vega-Rubin-de-Celis

doi:10.3389/fcell.2022.891332

Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective

Zhenyi An
, Wei Chung Chiang
, Álvaro F. Fernández
, Luis H. Franco
, Cong Cong He
, Shu Yi Huang
, Eunmyong Lee
, Yang Liu
, Salwa Sebti
, Sanae Shoji-Kawata
, Shyam Sirasanagandla
, Richard C. Wang
, Yongjie Wei
, Yuting Zhao
, Silvia Vega-Rubin-de-Celis^*

^*此作品的通信作者

生化暨分子生物研究所

研究成果: Review article › 同行評審

2 引文斯高帕斯（Scopus）

摘要

With great sadness, the scientific community received the news of the loss of Beth Levine on 15 June 2020. Dr. Levine was a pioneer in the autophagy field and work in her lab led not only to a better understanding of the molecular mechanisms regulating the pathway, but also its implications in multiple physiological and pathological conditions, including its role in development, host defense, tumorigenesis, aging or metabolism. This review does not aim to provide a comprehensive view of autophagy, but rather an outline of some of the discoveries made by the group of Beth Levine, from the perspective of some of her own mentees, hoping to honor her legacy in science.

原文	English
文章編號	891332
期刊	Frontiers in Cell and Developmental Biology
卷	10
DOIs	https://doi.org/10.3389/fcell.2022.891332
出版狀態	Published - 27 6月 2022

UN SDG

此研究成果有助於以下永續發展目標

SDG 3 良好的健康和福祉

存取文件

10.3389/fcell.2022.891332

其它文件與鏈接

Link to publication in Scopus

引用此

An, Z., Chiang, W. C., Fernández, Á. F., Franco, L. H., He, C. C., Huang, S. Y., Lee, E., Liu, Y., Sebti, S., Shoji-Kawata, S., Sirasanagandla, S., Wang, R. C., Wei, Y., Zhao, Y., & Vega-Rubin-de-Celis, S. (2022). Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective. Frontiers in Cell and Developmental Biology, 10, 文章 891332. https://doi.org/10.3389/fcell.2022.891332

@article{bf0f478c94f748608c8d21b337062365,

title = "Beth Levine{\textquoteright}s Legacy: From the Discovery of BECN1 to Therapies. A Mentees{\textquoteright} Perspective",

abstract = "With great sadness, the scientific community received the news of the loss of Beth Levine on 15 June 2020. Dr. Levine was a pioneer in the autophagy field and work in her lab led not only to a better understanding of the molecular mechanisms regulating the pathway, but also its implications in multiple physiological and pathological conditions, including its role in development, host defense, tumorigenesis, aging or metabolism. This review does not aim to provide a comprehensive view of autophagy, but rather an outline of some of the discoveries made by the group of Beth Levine, from the perspective of some of her own mentees, hoping to honor her legacy in science.",

keywords = "BECN1, Beth Levine, aging, cancer, infectious diseases, macroautophagy, metabolism, selective autophagy",

author = "Zhenyi An and Chiang, \{Wei Chung\} and Fern{\'a}ndez, \{{\'A}lvaro F.\} and Franco, \{Luis H.\} and He, \{Cong Cong\} and Huang, \{Shu Yi\} and Eunmyong Lee and Yang Liu and Salwa Sebti and Sanae Shoji-Kawata and Shyam Sirasanagandla and Wang, \{Richard C.\} and Yongjie Wei and Yuting Zhao and Silvia Vega-Rubin-de-Celis",

note = "Publisher Copyright: Copyright {\textcopyright} 2022 An, Chiang, Fern{\'a}ndez, Franco, He, Huang, Lee, Liu, Sebti, Shoji-Kawata, Sirasanagandla, Wang, Wei, Zhao and Vega-Rubin-de-Celis.",

year = "2022",

month = jun,

day = "27",

doi = "10.3389/fcell.2022.891332",

language = "English",

volume = "10",

journal = "Frontiers in Cell and Developmental Biology",

issn = "2296-634X",

publisher = "Frontiers Media SA",

}

An, Z, Chiang, WC, Fernández, ÁF, Franco, LH, He, CC, Huang, SY, Lee, E, Liu, Y, Sebti, S, Shoji-Kawata, S, Sirasanagandla, S, Wang, RC, Wei, Y, Zhao, Y & Vega-Rubin-de-Celis, S 2022, 'Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective', Frontiers in Cell and Developmental Biology, 卷 10, 891332. https://doi.org/10.3389/fcell.2022.891332

TY - JOUR

T1 - Beth Levine’s Legacy

T2 - From the Discovery of BECN1 to Therapies. A Mentees’ Perspective

AU - An, Zhenyi

AU - Chiang, Wei Chung

AU - Fernández, Álvaro F.

AU - Franco, Luis H.

AU - He, Cong Cong

AU - Huang, Shu Yi

AU - Lee, Eunmyong

AU - Liu, Yang

AU - Sebti, Salwa

AU - Shoji-Kawata, Sanae

AU - Sirasanagandla, Shyam

AU - Wang, Richard C.

AU - Wei, Yongjie

AU - Zhao, Yuting

AU - Vega-Rubin-de-Celis, Silvia

PY - 2022/6/27

Y1 - 2022/6/27

N2 - With great sadness, the scientific community received the news of the loss of Beth Levine on 15 June 2020. Dr. Levine was a pioneer in the autophagy field and work in her lab led not only to a better understanding of the molecular mechanisms regulating the pathway, but also its implications in multiple physiological and pathological conditions, including its role in development, host defense, tumorigenesis, aging or metabolism. This review does not aim to provide a comprehensive view of autophagy, but rather an outline of some of the discoveries made by the group of Beth Levine, from the perspective of some of her own mentees, hoping to honor her legacy in science.

AB - With great sadness, the scientific community received the news of the loss of Beth Levine on 15 June 2020. Dr. Levine was a pioneer in the autophagy field and work in her lab led not only to a better understanding of the molecular mechanisms regulating the pathway, but also its implications in multiple physiological and pathological conditions, including its role in development, host defense, tumorigenesis, aging or metabolism. This review does not aim to provide a comprehensive view of autophagy, but rather an outline of some of the discoveries made by the group of Beth Levine, from the perspective of some of her own mentees, hoping to honor her legacy in science.

KW - BECN1

KW - Beth Levine

KW - aging

KW - cancer

KW - infectious diseases

KW - macroautophagy

KW - metabolism

KW - selective autophagy

UR - https://www.scopus.com/pages/publications/85133925331

U2 - 10.3389/fcell.2022.891332

DO - 10.3389/fcell.2022.891332

M3 - Review article

AN - SCOPUS:85133925331

SN - 2296-634X

VL - 10

JO - Frontiers in Cell and Developmental Biology

JF - Frontiers in Cell and Developmental Biology

M1 - 891332

ER -

Beth Levine’s Legacy: From the Discovery of BECN1 to Therapies. A Mentees’ Perspective

摘要

UN SDG

存取文件

其它文件與鏈接

指紋

引用此