Bench to bedside review: Possible role of vitamin D in autism spectrum disorder

Feiyong Jia, Ling Shan, Bing Wang, Honghua Li, Chunyue Miao, Zhida Xu, Ching Po Lin, Khaled Saad*

*此作品的通信作者

研究成果: Review article同行評審

34 引文 斯高帕斯(Scopus)

摘要

Autism spectrum disorder (ASD) is a group of dysfunctions in social interaction, communication, and behaviors. Studies have demonstrated that vitamin D deficiency during pregnancy and in individuals increased the risk of ASD. A genetic polymorphism study has pinpointed that genotype AA/A-allele of GC rs4588 in children is associated with ASD, which encodes the vitamin D binding protein. Translating the mentioned points into clinical practice, several clinical trials have demonstrated that vitamin D supplementation can improve the core symptoms in children with ASD. One paper also showed that possible prophylactic effect for the reoccurrence of ASD by vitamin D supplement during pregnancy and early childhood. Herein, this review aims to address the recent advances in this field and to clarify the possible role of vitamin D in ASD.

原文English
頁(從 - 到)360-365
頁數6
期刊Psychiatry Research
260
DOIs
出版狀態Published - 2月 2018

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