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Astrocytic aryl hydrocarbon receptor mediates chronic kidney disease-associated mental disorders involving GLT1 hypofunction and neuronal activity enhancement in the mouse brain
Yu Jie Huang
, Chia Chi Hung
, Pei Chien Hsu
, Po Yi Lee
, Yen An Tsai
, Yu Chiao Hsin
, Xie Ting Lee
, Chia Cheng Chou
,
Mei Lien Chen
, Der Cherng Tarng
,
Yi Hsuan Lee
*
*
此作品的通信作者
環境與職業衛生研究所
生理學研究所
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引文 斯高帕斯(Scopus)
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Keyphrases
5/6 Nephrectomy
11%
Activity Enhancement
100%
Anterior Cingulate Cortex
22%
Anterior Cortex
11%
Antioxidant
11%
Aryl Hydrocarbon Receptor
100%
Aryl Hydrocarbon Receptor Antagonist
11%
Astrocytes
11%
Astrocytic
100%
Brain Disorders
11%
C-Fos
11%
Chronic Kidney Disease
100%
Cortical Culture
11%
Disease-associated
100%
Glia
11%
Glutamate Transporter 1 (GLT-1)
100%
Hemodialysis
11%
Hippocampal CA1 Region
11%
HO-1 Expression
11%
Hypofunction
100%
Indoxyl Sulfate
66%
Induced Disturbance
11%
Intranasal
11%
Knock-in Mouse Model
11%
Lineage-specific
11%
Memory Impairment
11%
Mental Disorders
100%
Mix Culture
11%
Mouse Brain
100%
Mouse Model
11%
Neural Lineage
11%
Neuronal Activity
100%
NOX1
11%
Oxidative Stress
11%
Perineuronal
22%
Primary Astrocytes
11%
Pro-oxidant
11%
Receptor Activation
11%
Receptor-independent
11%
Sulfate Concentration
11%
Sulfur Treatment
22%
Neuroscience
Agonist
10%
Anterior Cingulate Cortex
20%
Antioxidant
10%
Aryl Hydrocarbon Receptor
100%
Astrocyte
40%
Brain Disease
20%
C-Fos
10%
Glia
20%
Memory Disorder
10%
Mental Disorder
100%
Mouse Brain
100%
Neuronal Activity
100%
Oxidative Stress
10%
Oxidizing Agent
10%
Receptor Antagonist
10%
Vesicular Glutamate Transporter 1
100%
Pharmacology, Toxicology and Pharmaceutical Science
Antioxidant
10%
Aromatic Hydrocarbon Receptor
100%
Brain Disease
10%
Chronic Kidney Failure
100%
Endogenous Agonist
10%
Hemodialysis
10%
Indican
60%
Knockout Mouse
10%
Memory Disorder
10%
Mouse Model
10%
Oxidizing Agent
10%
Receptor Antagonist
10%
Vesicular Glutamate Transporter 1
100%