@article{f3bb656a2c094d5d8f5b3189d283c7e2,
title = "Aryl λ3-Iodane-Mediated 6-exo-trig Cyclization to Synthesize Highly Substituted Chiral Morpholines",
abstract = "A mild and efficient transition metal-free approach has been developed for the synthesis of highly substituted chiral morpholines from alkenols by amino acid-derived iodine(III) reagents via a 6-exo-trig cyclization. The key features of this work include the formation of three chiral centers with a high diastereomeric ratio, broad functional group compatibility, and atom/time economic methodology.",
keywords = "6-exo-trig cyclization, alkenes, halo-etherification, morpholines, λ-iodanes",
author = "Jaya Kishorevandavasi and Hu, {Wan Ping} and Gopal Chandrusenadi and Chen, {Hui Ting} and Chen, {Hsing Yin} and Hsieh, {Kuang Chan} and Wang, {Jeh Jeng}",
note = "Publisher Copyright: {\textcopyright} 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",
year = "2015",
month = sep,
day = "1",
doi = "10.1002/adsc.201500177",
language = "English",
volume = "357",
pages = "2788--2794",
journal = "Advanced Synthesis and Catalysis",
issn = "1615-4150",
publisher = "Wiley-VCH Verlag",
number = "13",
}