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Aromatic residues in RNase T stack with nucleobases to guide the sequence-specific recognition and cleavage of nucleic acids
Yulander Duh,
Yu Yuan Hsiao
, Chia Lung Li,
Jason C. Huang
, Hanna S. Yuan
*
*
此作品的通信作者
分子醫學與生物工程研究所
醫學生物技術暨檢驗學系
研究成果
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同行評審
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引文 斯高帕斯(Scopus)
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Keyphrases
Aromatic Residues
100%
Nucleobases
100%
Nucleic Acids
100%
RNase T
100%
Sequence-specific Recognition
100%
Phenylalanine
37%
Sequence Specificity
37%
Stacking Interactions
25%
Single-stranded DNA (ssDNA)
25%
3-terminal
25%
Protein Stability
12%
DNA Binding
12%
Tryptophan
12%
Thermal Stability
12%
Crystal Structure Analysis
12%
Sequence-dependent
12%
Tyrosine
12%
Escherichia Coli Strains
12%
DNA Complex
12%
3' End
12%
Exonuclease
12%
Exonuclease Activity
12%
Specific Activity
12%
Slow Growth
12%
Specificity Protein 1
12%
Dinucleotide
12%
Growth Phenotype
12%
Similar Sequences
12%
Single Guide RNA (sgRNA)
12%
Unique Sequences
12%
DNA Enzyme
12%
Sequence Preference
12%
RNA Enzyme
12%
Protein-nucleic Acid Recognition
12%
DNA Digestion
12%
T-DNA
12%
Biochemistry, Genetics and Molecular Biology
Nucleobase
100%
Nucleic Acid
100%
Ribonuclease
100%
Wild Type
37%
Phenylalanine
37%
RNA
25%
Exonuclease
25%
Protein Stability
12%
DNA Binding
12%
Enzyme
12%
Crystal Structure
12%
Escherichia coli
12%
Structure Analysis
12%
Tyrosine
12%
Thermostability
12%
Binding Affinity
12%
Tryptophan
12%
Immunology and Microbiology
Wild Type
100%
Escherichia coli
33%
Crystal Structure
33%
DNA Binding
33%
Protein Stability
33%
Binding Affinity
33%
Thermostability
33%