Application of Metal-Enhanced Fluorescence technology in evanescent wave fluorescent biosensor

Yu Zheng Su*, Min Wei Hung, Wen Hong Wu, Kuo Cheng Huang, Huihua Kenny Chiang

*此作品的通信作者

研究成果: Conference contribution同行評審

2 引文 斯高帕斯(Scopus)

摘要

Evanescent wave fluorescent sensors have developed for 30 years. Nonetheless, the technology continues to evolve with new breakthroughs in optics, biochemistry, and chemical engineering. Recently, there have been explosive developments in the Metal-Enhanced Fluorescence (MEF) technology to favorably modify the spectral properties and to alleviate photo-physical constraints. We report the development of core-shell nanoparticles with the silver core and SiO2 shell for potential applications in fiber optic biosensor. The fluorescence intensity of the fluorescence probe (Fluorescein isothiocyanate, FITC) doped core-shell nanoparticles was approximately 50-fold higher than that without core-shell nanoparticles doping. In addition, four different kinds of organic solvents are used in this study and found to have influence on the fluorescence intensity from 1.3 to over 100 times. We conclude that core-shell nanoparticles have capability to enhance the fiber optic sensing through amplifying fluorescence intensity and expect that their potential applications are used in a variety of biological applications.

原文English
主出版物標題2010 IEEE International Instrumentation and Measurement Technology Conference, I2MTC 2010 - Proceedings
頁面574-578
頁數5
DOIs
出版狀態Published - 2010
事件2010 IEEE International Instrumentation and Measurement Technology Conference, I2MTC 2010 - Austin, TX, United States
持續時間: 3 5月 20106 5月 2010

出版系列

名字2010 IEEE International Instrumentation and Measurement Technology Conference, I2MTC 2010 - Proceedings

Conference

Conference2010 IEEE International Instrumentation and Measurement Technology Conference, I2MTC 2010
國家/地區United States
城市Austin, TX
期間3/05/106/05/10

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